Catalog No.
PHK59001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SMARCC1 (Thr40-Asn277).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1, SWI/SNF complex subunit SMARCC1, BAF155, SMARCC1, BRG1-associated factor 155, SWI/SNF complex 155 kDa subunit
Purification
Purified by antigen affinity column.
Accession
Q92922
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
SWI/SNF protein expression status in fumarate hydratase-deficient renal cell carcinoma: immunohistochemical analysis of 32 tumors from 28 patients., PMID:29689242
Reactivity of human AGO2 monoclonal antibody 11A9 with the SWI/SNF complex: A case study for rigorously defining antibody selectivity., PMID:28779093
Loss of expression of the SWI/SNF complex is a frequent event in undifferentiated/dedifferentiated urothelial carcinoma of the urinary tract., PMID:27339451
Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression., PMID:20935679
SMARCC1 expression is upregulated in prostate cancer and positively correlated with tumour recurrence and dedifferentiation., PMID:18581278
Expression of SRG3, a chromatin-remodelling factor, in the mouse oocyte and early preimplantation embryos., PMID:17462105
Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt., PMID:16568092
Monoclonal antibodies reactive with the BAF155 (SMARCC1) and BAF170 (SMARCC2) components of human SWI/SNF-related complexes., PMID:15785210
p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes., PMID:9584200
Diversity and specialization of mammalian SWI/SNF complexes., PMID:8804307
For research use only. Not for human or drug use.
