Anti-Human HSD3B2 Polyclonal Antibody

Catalog No.

PHD70701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HSD3B2 (Met1-Pro286).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

3-beta-hydroxy-5-ene steroid dehydrogenase, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II, Progesterone reductase, 3-beta-HSD adrenal and gonadal type, HSDB3B, 3-beta-HSD II, HSD3B2, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2, Delta-5-3-ketosteroid isomerase

Purification

Purified by antigen affinity column.

Accession

P26439

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Roles of GDF9 and BMP15 in equine follicular development: in vivo content and in vitro effects of IGF1 and cortisol on granulosa cells., PMID:40289073

Microbiota modulates the steroid response to acute immune stress in male mice., PMID:38361932

Unexpected role of the human cytomegalovirus contribute to essential hypertension in the Kazakh Chinese population of Xinjiang., PMID:29752343

Development of monoclonal antibodies against the human 3β-hydroxysteroid dehydrogenase/isomerase isozymes., PMID:28863887

Disordered zonal and cellular CYP11B2 enzyme expression in familial hyperaldosteronism type 3., PMID:27793677

Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison's Disease)., PMID:26618927

Isoform-specific monoclonal antibodies against 3β-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism., PMID:24423300

Insulin-like growth factor 3 regulates expression of genes encoding steroidogenic enzymes and key transcription factors in the Nile tilapia gonad., PMID:22337331

Testosterone response of hepatic gene expression in female mice having acquired testosterone-unresponsive immunity to Plasmodium chabaudi malaria., PMID:21669218

Interleukins 1α and 1β as regulators of steroidogenesis in human NCI-H295R adrenocortical cells., PMID:21600230

Development of steroid signaling pathways during primordial follicle formation in the human fetal ovary., PMID:21430025

Human adrenal cells that express both 3β-hydroxysteroid dehydrogenase type 2 (HSD3B2) and cytochrome b5 (CYB5A) contribute to adrenal androstenedione production., PMID:21185375

Inhibitory effects of cholesterol sulfate on progesterone production in human granulosa-like tumor cell line, KGN., PMID:18490834

A case of 3beta-hydroxysteroid dehydrogenase type II (HSD3B2) deficiency picked up by neonatal screening for 21-hydroxylase deficiency: difficulties and delay in etiologic diagnosis., PMID:17496421

YY1 binding within the human HSD3B2 gene intron 1 is required for maximal basal promoter activity: identification of YY1 as the 3beta1-A factor., PMID:15291746

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