Catalog No.
PHK55101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human VANGL2 (Gln241-Lys493).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
STB1, VANGL2, Van Gogh-like protein 2, Loop-tail protein 1 homolog, KIAA1215, Vang-like protein 2, Strabismus 1
Purification
Purified by antigen affinity column.
Accession
Q9ULK5
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Analysis of the Ubiquitination and Phosphorylation of Vangl Proteins., PMID:36353719
Planar cell polarity signaling components are a direct target of β-amyloid-associated degeneration of glutamatergic synapses., PMID:34407949
β1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs., PMID:33051257
Domineering non-autonomy in Vangl1;Vangl2 double mutants demonstrates intercellular PCP signaling in the vertebrate inner ear., PMID:29510119
The Major Histocompatibility Complex Class III Haplotype Ltab-Ncr3 Regulates Adjuvant-Induced but Not Antigen-Induced Autoimmunity., PMID:28315676
Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance., PMID:27955617
The planar cell polarity protein Vangl2 is required for retinal axon guidance., PMID:25990804
Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury., PMID:25145929
Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes., PMID:23029439
The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation., PMID:20843830
Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure., PMID:19966784
WNT/PCP signaling pathway and human cancer (review)., PMID:16273260