Catalog No.
PHK54101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NHEJ1 (Met1-Ser127).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Non-homologous end-joining factor 1, XRCC4-like factor, NHEJ1, XLF, Protein cernunnos
Purification
Purified by antigen affinity column.
Accession
Q9H9Q4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology., PMID:34056803
Structural basis of long-range to short-range synaptic transition in NHEJ., PMID:33854234
Extreme Phenotypes With Identical Mutations: Two Patients With Same Non-sense NHEJ1 Homozygous Mutation., PMID:30666249
PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line., PMID:27601633
XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination., PMID:27281794
Dynamic changes in subcellular localization of cattle XLF during cell cycle, and focus formation of cattle XLF at DNA damage sites immediately after irradiation., PMID:25947322
Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis., PMID:22312109
A primary immunodeficiency characterized by defective immunoglobulin class switch recombination and impaired DNA repair., PMID:17485519
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly., PMID:16439204
For research use only. Not for human or drug use.
