Anti-Human CBX5 Polyclonal Antibody

Catalog No.

PHE45601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CBX5 (Gly2-Lys80).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Heterochromatin protein 1 homolog alpha, Chromobox protein homolog 5, HP1A, Antigen p25, HP1 alpha, CBX5

Purification

Purified by antigen affinity column.

Accession

P45973

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

In vitro expression of precore proteins of hepatitis B virus subgenotype A1 is affected by HBcAg, and can affect HBsAg secretion., PMID:33854155

A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: Lipidation and polyelectrolyte complexes., PMID:33120079

Blood or skin: what is best in predicting cow's milk allergy diagnosis?, PMID:31789491

A Viral-Vectored Multi-Stage Malaria Vaccine Regimen With Protective and Transmission-Blocking Efficacies., PMID:31681301

A Multi-Stage Plasmodium vivax Malaria Vaccine Candidate Able to Induce Long-Lived Antibody Responses Against Blood Stage Parasites and Robust Transmission-Blocking Activity., PMID:31119106

Accuracy of the median channel shift in the flow cytometry for predicting complement dependent cytotoxicity crossmatching in kidney transplant candidates., PMID:30367965

Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction., PMID:29464021

Large-Scale Identification of Protein Crotonylation Reveals Its Role in Multiple Cellular Functions., PMID:28234478

Study of the clinical relevance of Helicobacter pylori virulence genes to gastric diseases among Egyptian patients., PMID:27344093

Transmission blocking potency and immunogenicity of a plant-produced Pvs25-based subunit vaccine against Plasmodium vivax., PMID:27177945

Anticentromere antibody-positive primary Sjögren's syndrome: Epitope analysis of a subset of anticentromere antibody-positive patients., PMID:27161330

Metastasis-associated protein ribosomal RNA processing 1 homolog B (RRP1B) modulates metastasis through regulation of histone methylation., PMID:25092915

Autoantibodies to the Rpp25 component of the Th/To complex are the most common antibodies in patients with systemic sclerosis without antibodies detectable by widely available commercial tests., PMID:24931955

Prevalence, diagnostic value and clinical characteristics associated with the presence of circulating levels and renal deposits of antibodies against the M-type phospholipase A2 receptor in idiopathic membranous nephropathy., PMID:24798555

Dynamic phosphorylation of HP1α regulates mitotic progression in human cells., PMID:24619172

Clinical significance of autoantibodies to the pericentromeric heterochromatin protein 1a protein., PMID:24184038

Protein A immunosensor for the detection of immunoglobulin G by impedance spectroscopy., PMID:24141418

p10, the N-terminal domain of p35, protects against CDK5/p25-induced neurotoxicity., PMID:23151508

Immunological evaluation of lipopeptide group A streptococcus (GAS) vaccine: structure-activity relationship., PMID:22253911

Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1{alpha} localization in erythroblasts., PMID:21364188

Serodiagnosis of borreliosis: indirect immunofluorescence assay, enzyme-linked immunosorbent assay and immunoblotting., PMID:21258869

HP1α is not necessary for the structural maintenance of centromeric heterochromatin., PMID:20962594

Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritis., PMID:20955560

Heterochromatin marks HP1γ, HP1α and H3K9me3, and DNA damage response activation in human testis development and germ cell tumours., PMID:20695923

A very large C-loop in EGF domain IV is characteristic of the P28 family of ookinete surface proteins., PMID:19057932

CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice., PMID:18606155

The heterochromatin protein 1 family is regulated in prostate development and cancer., PMID:18436254

Protection against heterologous human papillomavirus challenge by a synthetic lipopeptide vaccine containing a broadly cross-neutralizing epitope of L2., PMID:18413606

Pre-Lamin A processing is linked to heterochromatin organization., PMID:17654502

[Recent research on the JC virus]., PMID:17380774

The brain-specific protein TPPP/p25 in pathological protein deposits of neurodegenerative diseases., PMID:17123092

The use of transgenic Plasmodium berghei expressing the Plasmodium vivax antigen P25 to determine the transmission-blocking activity of sera from malaria vaccine trials., PMID:17049690

Phosphorylation of the linker histone H1 by CDK regulates its binding to HP1alpha., PMID:16762841

Truncated HP1 lacking a functional chromodomain induces heterochromatinization upon in vivo targeting., PMID:16283356

Leptospiral proteins expressed during acute & convalescent phases of human leptospirosis., PMID:15489552

Histone modification in constitutive heterochromatin versus unexpressed euchromatin in human cells., PMID:15368356

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance., PMID:15215892

Serological description of Estonian patients with Lyme disease, a comparison with control sera from endemic and non-endemic areas., PMID:15147004

Effects of cyclin-dependent kinase-5 activity on apoptosis and tau phosphorylation in immortalized mouse brain cortical cells., PMID:15048935

NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin., PMID:14742713

Analysis of egg antigens inducing hepatic lesions in schistosome infection., PMID:14665394

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns., PMID:14519686

Cell cycle behavior of human HP1 subtypes: distinct molecular domains of HP1 are required for their centromeric localization during interphase and metaphase., PMID:12840071

HP1beta and HP1gamma, but not HP1alpha, decorate the entire XY body during human male meiosis., PMID:12675308

MUM1/IRF4 expression is an unfavorable prognostic factor in B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL)., PMID:12079517

Immunolocalization of HP1 proteins in metaphasic mammalian chromosomes., PMID:11741155

Design and synthesis of potent and selective alpha(4)beta(7) integrin antagonists., PMID:11472212

Transcriptional repression mediated by the KRAB domain of the human C2H2 zinc finger protein Kox1/ZNF10 does not require histone deacetylation., PMID:11405226

HP1gamma associates with euchromatin and heterochromatin in mammalian nuclei and chromosomes., PMID:11124534

Immunohistochemical versus molecular detection of RAK antigens in breast cancer., PMID:10891290

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