Catalog No.
PHK49601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MSI2 (Lys22-Ala96).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Musashi-2, RNA-binding protein Musashi homolog 2, MSI2
Purification
Purified by antigen affinity column.
Accession
Q96DH6
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
MSI2 promotes translation of multiple IRES-containing oncogenes and virus to induce self-renewal of tumor initiating stem-like cells., PMID:37117191
CEBPA mutants down-regulate AML cell susceptibility to NK-mediated lysis by disruption of the expression of NKG2D ligands, which can be restored by LSD1 inhibition., PMID:35003895
MUSASHI-2 confers resistance to third-generation EGFR-tyrosine kinase inhibitor osimertinib in lung adenocarcinoma., PMID:34145929
Musashi2 contributes to the maintenance of CD44v6+ liver cancer stem cells via notch1 signaling pathway., PMID:31888685
Genomic data integration in chronic lymphocytic leukemia., PMID:27928896
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs., PMID:24395885
Drosophila Rbp6 is an orthologue of vertebrate Msi-1 and Msi-2, but does not function redundantly with dMsi to regulate germline stem cell behaviour., PMID:23209605
For research use only. Not for human or drug use.
