Anti-Human SERPINH1 Polyclonal Antibody

Catalog No.

PHE76601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SERPINH1 (Leu36-Leu418).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Colligin, CBP1, CBP2, SERPINH1, SERPINH2, Rheumatoid arthritis-related antigen RA-A47, Cell proliferation-inducing gene 14 protein, 47 kDa heat shock protein, Serpin H1, AsTP3, HSP47, Collagen-binding protein, Arsenic-transactivated protein 3

Purification

Purified by antigen affinity column.

Accession

P50454

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Inhibition of heat shock protein 47 suppressed collagen production in Tenon's capsule fibroblasts., PMID:37724035

Identification of key genes in colorectal cancer diagnosis by co-expression analysis weighted gene co-expression network analysis., PMID:36931200

Investigating the role of heat shock protein 47 in fibrosis in Crohn's disease., PMID:35768471

Gold Nanostars Combined with the Searched Antibody for Targeted Oral Squamous Cell Carcinoma Therapy., PMID:35603744

A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer., PMID:34215253

Periodontal bacteria and the rheumatoid arthritis-related antigen RA-A47: the cross-reactivity potential., PMID:31356381

Markers of graft microvascular endothelial injury may identify harmful donor-specific anti-HLA antibodies and predict kidney allograft loss., PMID:30836425

Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease., PMID:29363541

[Single-chain human anti-EGFR antibody/truncated protamine fusion protein carrying Hsp47 siRNA can induce apoptosis of human hepatic stellate cells]., PMID:25531382

Quantitative comparison of tumor delivery for multiple targeted nanoparticles simultaneously by multiplex ICP-MS., PMID:25068300

High expression of HSP47 in ulcerative colitis-associated carcinomas: proteomic approach., PMID:19603022

Remodeling of the rat gingiva induced by CO2 laser coagulation mode., PMID:19065560

Immunohistochemical distribution of heat shock protein 47 (HSP47) in scirrhous carcinoma of the stomach., PMID:16475681

Water-soluble polymers for targeted drug delivery to human squamous carcinoma of head and neck., PMID:16036307

Autoantibodies to a collagen-specific molecular chaperone, heat-shock protein 47, in systemic sclerosis., PMID:15544633

Accumulation of type IV collagen in dilated ER leads to apoptosis in Hsp47-knockout mouse embryos via induction of CHOP., PMID:15522896

Downregulation of rheumatoid arthritis-related antigen RA-A47 (HSP47/colligin-2) in chondrocytic cell lines induces apoptosis and cell-surface expression of RA-A47 in association with CD9., PMID:15389525

Acute allergen-induced airway remodeling in atopic asthma., PMID:15333330

Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy., PMID:15004023

Dendritic cells in neointima formation after rat carotid balloon injury: coordinated expression withanti-apoptotic Bcl-2 and HSP47 in arterial repair., PMID:12957445

Targeting of human squamous carcinomas by SPA470-doxorubicin immunoconjugates., PMID:12881196

Prevalence of HSP47 antigen and autoantibodies to HSP47 in the sera of patients with mixed connective tissue disease., PMID:12659832

Sec61alpha synthesis is enhanced during translocation of nascent chains of collagen type IV in F9 teratocarcinoma cells after retinoic acid treatment., PMID:12532224

The renal expression of heat shock protein 47 and collagens in acute and chronic experimental diabetes in rats., PMID:12197670

Extracellular matrix components in a case of retrocorneal membrane associated with syphilitic interstitial keratitis., PMID:11188990

Involvement of collagen-binding heat shock protein 47 and procollagen type I synthesis in idiopathic pulmonary fibrosis: contribution of type II pneumocytes to fibrosis., PMID:11150375

Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat., PMID:11141481

Rheumatoid arthritis-related antigen 47kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47., PMID:11052465

Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation., PMID:10916082

Increase in expression of Hsp47 and collagen in hereditary gingival fibromatosis is modulated by stress and terminal procollagen N-propeptides., PMID:10757112

Detection of specific antibodies against human cultured chondrosarcoma (HCS-2/8) and osteosarcoma (Saos-2) cells in the serum of patients with osteoarthritis of the temporomandibular joint., PMID:10391498

Cell surface colligin/Hsp47 associates with tetraspanin protein CD9 in epidermoid carcinoma cell lines., PMID:10227388

Immunolocalization of collagen and collagen-binding heat shock protein 47 in fibrotic lung diseases., PMID:9872649

Coexpression of collagens and collagen-binding heat shock protein 47 in human diabetic nephropathy and IgA nephropathy., PMID:9832643

Expression of heat shock protein 47 is increased in remnant kidney and correlates with disease progression., PMID:9741355

Antisense oligonucleotides against collagen-binding stress protein HSP47 suppress collagen accumulation in experimental glomerulonephritis., PMID:9714184

Hsp47 binds to the KDEL receptor and cell surface expression is modulated by cytoplasmic and endosomal pH., PMID:9643651

The retention of abnormal type I procollagen and correlated expression of HSP 47 in fibroblasts from a patient with lethal osteogenesis imperfecta., PMID:9602714

Isolation and characterization of a rheumatoid arthritis-specific antigen (RA-A47) from a human chondrocytic cell line (HCS-2/8)., PMID:9588174

Collagen-binding heat shock protein (HSP) 47 expression in anti-thymocyte serum (ATS)-induced glomerulonephritis., PMID:9370943

Intracellular distribution of heat-induced stress glycoproteins., PMID:9215532

Intracellular interaction of collagen-specific stress protein HSP47 with newly synthesized procollagen., PMID:8609177

Endoplasmic reticulum protein Hsp47 binds specifically to the N-terminal globular domain of the amino-propeptide of the procollagen I alpha 1 (I)-chain., PMID:8567753

Marked induction of HSP47, a collagen-binding stress protein, during solid tumor formation of ascitic Sarcoma 180 in vivo., PMID:8900930

Hsp47 and cyclophilin B traverse the endoplasmic reticulum with procollagen into pre-Golgi intermediate vesicles. A role for Hsp47 and cyclophilin B in the export of procollagen from the endoplasmic reticulum., PMID:7629154

Regulation of J6 gene expression by transcription factor GATA-4., PMID:7717974

Age-related attenuation of HSP47 heat response in fibroblasts., PMID:7739268

HSP47 as a possible marker for malignancy of tumors in vivo., PMID:7803705

Dynamic variations in the expression of type I collagen and its molecular chaperone Hsp47 in cells of the mouse dental follicle during tooth eruption., PMID:8018053

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