Catalog No.
PHG74801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human FHL2 (Gly16-Ser98).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DRAL, FHL2, LIM domain protein DRAL, FHL-2, Skeletal muscle LIM-protein 3, Four and a half LIM domains protein 2, SLIM-3, SLIM3
Purification
Purified by antigen affinity column.
Accession
Q14192
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
FHL2 expression by cancer-associated fibroblasts promotes metastasis and angiogenesis in lung adenocarcinoma., PMID:39244734
Precise CRISPR-Cas9 gene repair in autologous memory T cells to treat familial hemophagocytic lymphohistiocytosis., PMID:38306418
The function of Lmpt in Drosophila heart tissue., PMID:35500437
The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma., PMID:34076685
Systemic and Nodular Hyperinflammation in a Patient with Refractory Familial Hemophagocytic Lymphohistiocytosis 2., PMID:33570715
FHL2 Is Essential for Spleen T Cell-Dependent B Cell Activation and Antibody Response., PMID:32434880
Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome., PMID:32028069
Tissue microarray profiling in human heart failure., PMID:27364902
FHL2: a scaffold protein of carcinogenesis, tumour-stroma interactions and treatment response., PMID:26676939
Expression and purification of GST-FHL2 fusion protein., PMID:24390986
Down-regulation of CD5 expression on activated CD8+ T cells in familial hemophagocytic lymphohistiocytosis with perforin gene mutations., PMID:24051121
Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer., PMID:23756870
Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates liver fibrosis in mice., PMID:23311569
Bioinformatics analysis of proteomic profiles during the process of anti-Thy1 nephritis., PMID:22159597
XIAP-associated factor 1 interacts with and attenuates the trans-activity of four and a Half LIM protein 2., PMID:21104993
Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1., PMID:20801642
The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone., PMID:19265191
The cell migration protein Grb7 associates with transcriptional regulator FHL2 in a Grb7 phosphorylation-dependent manner., PMID:18853468
Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis., PMID:18252802
Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy., PMID:17360664
Characterization of recombinant and natural forms of the human LIM domain-containing protein FHL2., PMID:14680945
Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2., PMID:12432079
Interaction of the heart-specific LIM domain protein, FHL2, with DNA-binding nuclear protein, hNP220., PMID:11813260
DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis., PMID:11062252
Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma., PMID:9150430
For research use only. Not for human or drug use.
