Anti-Human U2AF1 Polyclonal Antibody

Catalog No.

PHF85001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human U2AF1 (Met1-Arg196).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

U2AFBP, U2 auxiliary factor 35 kDa subunit, U2AF1, U2 snRNP auxiliary factor small subunit, U2 small nuclear RNA auxiliary factor 1, Splicing factor U2AF 35 kDa subunit, U2AF35

Purification

Purified by antigen affinity column.

Accession

Q01081

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Long-term longitudinal analysis of 4,187 participants reveals insights into determinants of clonal hematopoiesis., PMID:39251642

Activation of ERβ hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer., PMID:38513102

Advances in the Treatment of Hairy Cell Leukemia Variant., PMID:35178674

Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway., PMID:35081975

Classification and Personalized Prognostic Assessment on the Basis of Clinical and Genomic Features in Myelodysplastic Syndromes., PMID:33539200

Battle of the clones: paroxysmal nocturnal hemoglobinuria vs myelodysplastic syndrome., PMID:32533252

High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias., PMID:24241536

Differential expression of U2AF35 in the arthritic joint of avian reovirus-infected chicks., PMID:16916547

Substrate-dependent differences in U2AF requirement for splicing in adenovirus-infected cell extracts., PMID:15899895

PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor., PMID:15474994

Dual function for U2AF(35) in AG-dependent pre-mRNA splicing., PMID:11604503

The role of U2AF35 and U2AF65 in enhancer-dependent splicing., PMID:11421359

Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65)., PMID:10567551

Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit., PMID:1388271

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