Anti-Human TAX1BP1 Polyclonal Antibody

Catalog No.

PHK48801

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TAX1BP1 (His16-Lys146).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Tax1-binding protein 1, TAX1BP1, TRAF6-binding protein, T6BP

Purification

Purified by antigen affinity column.

Accession

Q86VP1

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

TAX1BP1-dependent autophagic degradation of STING1 impairs anti-tumor immunity., PMID:40000606

Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation., PMID:39508267

Cleavage of SQSTM1/p62 by the Zika virus protease NS2B3 prevents autophagic degradation of viral NS3 and NS5 proteins., PMID:39128850

CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity., PMID:38869076

Decreased TAX1BP1 participates in systemic lupus erythematosus by regulating monocyte/macrophage function., PMID:37465957

TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation., PMID:35266845

Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling., PMID:29358708

Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1., PMID:27515252

Immunization of mice with a peptide derived from the HTLV-1 TAX1BP1 protein induces cross-reactive antibodies against aquaporin 4., PMID:26287441

Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling., PMID:25774694

Crystallographic and modelling studies suggest that the SKICH domains from different protein families share a common Ig-like fold but harbour substantial structural variations., PMID:25187058

The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoprotein., PMID:23616667

TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling., PMID:23209807

The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1., PMID:21765415

Fine specificity of antibodies against AQP4: epitope mapping reveals intracellular epitopes., PMID:21333492

Gain of GRHL2 is associated with early recurrence of hepatocellular carcinoma., PMID:18752864

Tax1-binding protein 1 is expressed in the retina and interacts with the GABA(C) receptor rho1 subunit., PMID:16999686

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