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Anti-Human PRMT6 Polyclonal Antibody

Catalog #:   PHK48101 Specific References (8) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q96LA8
Overview

Catalog No.

PHK48101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PRMT6 (Arg82-Asp375).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6, Protein arginine N-methyltransferase 6, PRMT6, HRMT1L6

Purification

Purified by antigen affinity column.

Accession

Q96LA8

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN-BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with PRMT6 antibody (PHK48101) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 35 kDa
    Observed MW: 35 kDa
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with PRMT6 antibody (PHK48101) at 1 μg/ml.

    Lane 1: NCI-H460

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 42 kDa
    Observed MW: 42 kDa
  • Immunohistochemical
    Immunohistochemical analysis of mouse teratoma tissue stained for PRMT6 with PHK48101.
References

Inhibition of protein arginine methyltransferase 6 activates interferon signaling and induces the apoptosis of endometrial cancer cells via histone modification., PMID:38299254

Proteome-wide Profiling of Asymmetric Dimethylated Arginine in Human Breast Tumors., PMID:37463068

Genome-Wide Association Study Identifies Genomic Loci Associated With Neurotransmitter Concentration in Cattle., PMID:32292413

Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to the Transcriptional Outcome of Associated Genes., PMID:30232013

Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization., PMID:29471495

pUL69 of Human Cytomegalovirus Recruits the Cellular Protein Arginine Methyltransferase 6 via a Domain That Is Crucial for mRNA Export and Efficient Viral Replication., PMID:26178996

Regulation of post-translational protein arginine methylation during HeLa cell cycle., PMID:20541591

Thrombospondin-1 is a transcriptional repression target of PRMT6., PMID:19509293

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-Human PRMT6 Polyclonal Antibody [PHK48101]
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