Catalog No.
PHK48101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PRMT6 (Arg82-Asp375).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6, Protein arginine N-methyltransferase 6, PRMT6, HRMT1L6
Purification
Purified by antigen affinity column.
Accession
Q96LA8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Inhibition of protein arginine methyltransferase 6 activates interferon signaling and induces the apoptosis of endometrial cancer cells via histone modification., PMID:38299254
Proteome-wide Profiling of Asymmetric Dimethylated Arginine in Human Breast Tumors., PMID:37463068
Genome-Wide Association Study Identifies Genomic Loci Associated With Neurotransmitter Concentration in Cattle., PMID:32292413
Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to the Transcriptional Outcome of Associated Genes., PMID:30232013
Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization., PMID:29471495
pUL69 of Human Cytomegalovirus Recruits the Cellular Protein Arginine Methyltransferase 6 via a Domain That Is Crucial for mRNA Export and Efficient Viral Replication., PMID:26178996
Regulation of post-translational protein arginine methylation during HeLa cell cycle., PMID:20541591
Thrombospondin-1 is a transcriptional repression target of PRMT6., PMID:19509293