Catalog No.
PHK47301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DIO2 (Leu69-Leu269).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DIO2, TXDI2, ITDI2, Type II iodothyronine deiodinase, Type-II 5'-deiodinase, Type 2 DI, 5DII, DIOII
Purification
Purified by antigen affinity column.
Accession
Q92813
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders., PMID:39754930
Effects of the synthetic progestin levonorgestrel on some aspects of thyroid physiology in common carp (Cyprinus carpio)., PMID:36244424
A Type 2 Deiodinase-Dependent Increase in Vegfa Mediates Myoblast-Endothelial Cell Crosstalk During Skeletal Muscle Regeneration., PMID:32787533
Low CSF/serum ratio of free T4 is associated with decreased quality of life in mild hypothyroidism - A pilot study., PMID:32154116
Thyrotropin, but Not Thyroid-Stimulating Antibodies, Induces Biphasic Regulation of Gene Expression in Human Thyrocytes., PMID:31805824
Sirt1 Promotes a Thermogenic Gene Program in Bone Marrow Adipocytes: From Mice to (Wo)Men., PMID:30873124
Effect of antithyroid drugs on the occurrence of antibodies against type 2 deiodinase (DIO2), which are involved in hyperthyroid Graves' disease influencing the therapeutic efficacy., PMID:30610492
Study of Deiodinase Type 2 Polymorphisms in Graves' Disease and Ophthalmopathy in a Swedish Population., PMID:30574458
Deficiency of type 2 iodothyronine deiodinase reduces necroptosis activity and oxidative stress responses in retinas of Leber congenital amaurosis model mice., PMID:29874126
Maternal and placental responses before preterm birth: adaptations to increase fetal thyroid hormone availability?, PMID:29557697
Is the Intrinsic Genomic Activity of Thyroxine Relevant In Vivo? Effects on Gene Expression in Primary Cerebrocortical and Neuroblastoma Cells., PMID:28605984
Antibody-Mediated Inhibition of the FGFR1c Isoform Induces a Catabolic Lean State in Siberian Hamsters., PMID:26549257
[DIO2, TPO, CYP1A1 AND CYP1A2 gene polymorphism in women with thyroid disease]., PMID:25306702
Embryonic exposure to carbendazim induces the transcription of genes related to apoptosis, immunotoxicity and endocrine disruption in zebrafish (Danio rerio)., PMID:25304545
Detection of long-term influence of prenatal temperature stimulation on hypothalamic type-II iodothyronine deiodinase in juvenile female broiler chickens using a novel immunohistochemical amplification protocol., PMID:25289994
Evaluation of sex, race, body mass index and pre-vaccination serum progesterone levels and post-vaccination serum anti-anthrax protective immunoglobulin G on injection site adverse events following anthrax vaccine adsorbed (AVA) in the CDC AVA human clinical trial., PMID:24768633
Genes that characterize T3-predominant Graves' thyroid tissues., PMID:23109646
Increased type 3 deiodinase expression in papillary thyroid carcinoma., PMID:22823995
Histone modifications on the adrenergic induction of type II deiodinase in rat pinealocytes., PMID:21704117
Photoperiodic control of TSH-beta expression in the mammalian pars tuberalis has different impacts on the induction and suppression of the hypothalamo-hypopysial gonadal axis., PMID:19912473
Analysis of target genes induced by IL-13 cytotoxin in human glioblastoma cells., PMID:15803373
The human type 2 iodothyronine deiodinase is a selenoprotein highly expressed in a mesothelioma cell line., PMID:11425850
For research use only. Not for human or drug use.
