Catalog No.
PHK47201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CHMP2B (Lys8-Gly171).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Vacuolar protein sorting-associated protein 2-2, CHMP2B, CHMP2b, hVps2-2, CHMP2.5, Vps2-2, Charged multivesicular body protein 2b, Chromatin-modifying protein 2b
Purification
Purified by antigen affinity column.
Accession
Q9UQN3
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The identification of high-performing antibodies for Charged multivesicular body protein 2b for use in Western Blot, immunoprecipitation and immunofluorescence., PMID:37635943
Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation., PMID:35978952
Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B)., PMID:30414727
ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo., PMID:25008355
Molecular markers for granulovacuolar degeneration are present in rimmed vacuoles., PMID:24312256
Localization of CHMP2B-immunoreactivity in the brainstem of Lewy body disease., PMID:22989140
Cyclin-dependent kinase 5 immunoreactivity for granulovacuolar degeneration., PMID:22968343
Endosomal sorting related protein CHMP2B is localized in Lewy bodies and glial cytoplasmic inclusions in α-synucleinopathy., PMID:22947304
Immunopositivity for ESCRT-III subunit CHMP2B in granulovacuolar degeneration of neurons in the Alzheimer's disease hippocampus., PMID:20420883
Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations., PMID:20223751
Distinct genetic forms of frontotemporal dementia., PMID:18703462
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)., PMID:16807408
For research use only. Not for human or drug use.
