Catalog No.
PHH21501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human VAMP3 (Met1-Met78).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CEB, Synaptobrevin-3, Cellubrevin, VAMP3, VAMP-3, SYB3, Vesicle-associated membrane protein 3
Purification
Purified by antigen affinity column.
Accession
Q15836
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Multifunctional regulation of VAMP3 in exocytic and endocytic pathways of RBL-2H3 cells., PMID:35990647
Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study., PMID:35816651
Utility of extracellular vesicles as a potential biological indicator of physiological resilience during military operational stress., PMID:35373929
VAMPs sensitive to tetanus toxin are required for cortical granule exocytosis in mouse oocytes., PMID:34023392
Megakaryocytes package contents into separate α-granules that are differentially distributed in platelets., PMID:31648331
In human nephrectomy specimens, the kidney level of tubular transport proteins does not correlate with their abundance in urinary extracellular vesicles., PMID:31241991
The in vitro detection of botulinum neurotoxin-cleaved endogenous VAMP is epitope-dependent., PMID:29373835
Human Platelet Vesicles Exhibit Distinct Size and Proteome., PMID:28587468
Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation., PMID:27548575
Astrocyte VAMP3 vesicles undergo Ca2+ -independent cycling and modulate glutamate transporter trafficking., PMID:25864578
SNAP-23 and VAMP-3 contribute to the release of IL-6 and TNFα from a human synovial sarcoma cell line., PMID:24373201
Syntaxin-4 is essential for IgE secretion by plasma cells., PMID:24055037
SNAP-23 and syntaxin-3 are required for chemokine release by mature human mast cells., PMID:21981832
Glucose-dependent changes in SNARE protein levels in pancreatic β-cells., PMID:21285315
Aspirin regulates SNARE protein expression and phagocytosis in dendritic cells., PMID:21231793
Gamma-amino butyric acid (GABA) release in the ciliated protozoon Paramecium occurs by neuronal-like exocytosis., PMID:20348336
Targeting the epithelial SNARE machinery by bacterial neurotoxins., PMID:18369946
Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells., PMID:18253931
Auto-antibodies in prostate cancer: humoral immune response to antigenic determinants coded by the differentially expressed transcripts FLJ23438 and VAMP3., PMID:16897729
Testicular proteins associated with the germ cell-marker, TEX101: involvement of cellubrevin in TEX101-trafficking to the cell surface during spermatogenesis., PMID:16678124
Identification of soluble N-ethylmaleimide-sensitive factor attachment protein receptor exocytotic machinery in human plasma cells: SNAP-23 is essential for antibody secretion., PMID:16272324
ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages., PMID:12810696
Subcellular distribution of 3 functional platelet SNARE proteins: human cellubrevin, SNAP-23, and syntaxin 2., PMID:12010801
Endothelial transcytotic machinery involves supramolecular protein-lipid complexes., PMID:11294904
Identification of discrete classes of endosome-derived small vesicles as a major cellular pool for recycling membrane proteins., PMID:11294901
Localization of cellubrevin-related peptide, endobrevin, in the early endosome in pancreatic beta cells and its physiological function in exo-endocytosis of secretory granules., PMID:11112705
EGF triggers caveolin redistribution from the plasma membrane to the early/sorting endocytic compartment of hepatocytes., PMID:11027946
SNAP-25 regulation during adrenal gland development: comparison with differentiation markers and other SNAREs., PMID:10842212
Cellubrevin is present in the basolateral endocytic compartment of hepatocytes and follows the transcytotic pathway after IgA internalization., PMID:10713107
Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking., PMID:10564279
Cultured glial cells express the SNAP-25 analogue SNAP-23., PMID:10417817
Identification of a cellubrevin/vesicle associated membrane protein 3 homologue in human platelets., PMID:9885218
Cellubrevin-targeted fluorescence uncovers heterogeneity in the recycling endosomes., PMID:9677389
A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion., PMID:9425154
Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31., PMID:9396746
Immunohistochemical localization of cellubrevin on secretory granules in pancreatic B-cells., PMID:9376176
Identification of SNAP receptors in rat adipose cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein., PMID:8973549
Rab4 and cellubrevin define different early endosome populations on the pathway of transferrin receptor recycling., PMID:8790369
Localization of cellubrevin to the Golgi complex in pancreatic acinar cells., PMID:8864658
Cleavage of vesicle-associated membrane protein (VAMP)-2 and cellubrevin on GLUT4-containing vesicles inhibits the translocation of GLUT4 in 3T3-L1 adipocytes., PMID:8607835
Expression of synaptobrevin II, cellubrevin and syntaxin but not SNAP-25 in cultured astrocytes., PMID:8549782
Cellubrevin and synaptobrevins: similar subcellular localization and biochemical properties in PC12 cells., PMID:7698987
Expression of vesicle-associated membrane protein 2 (VAMP-2)/synaptobrevin II and cellubrevin in rat skeletal muscle and in a muscle cell line., PMID:7998925
Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells., PMID:8195285