Catalog No.
PHH07901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RHEB (Met1-Met184).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
RHEB2, Ras homolog enriched in brain, RHEB, GTP-binding protein Rheb
Purification
Purified by antigen affinity column.
Accession
Q15382
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
AP2M1 as the potential biomarker for prediction of the response of atopic dermatitis to Dupilumab therapy: Multi-omics analysis and evidence., PMID:39818381
Dihydroberberine alleviates Th17/Treg imbalance in premature ovarian insufficiency mice via inhibiting Rheb/mTOR signaling., PMID:39472803
Gastroprotective effects of polysaccharides from purple sweet potato (Ipomoea batatas (L.) Lam) on an ethanol-induced gastric ulcer via regulating immunity and activating the PI3K/Akt/Rheb/mTOR pathway., PMID:38726829
An autophagy-associated diagnostic signature based on peripheral blood for antibody-mediated rejection in renal transplantation., PMID:38452984
Constitutively active Rheb mutants [T23M] and [E40K] drive increased production and secretion of recombinant protein in Chinese hamster ovary cells., PMID:33694218
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis., PMID:29961810
Protection of nigral dopaminergic neurons by AAV1 transduction with Rheb(S16H) against neurotoxic inflammation in vivo., PMID:29422542
Evaluating the mTOR Pathway in Physiological and Pharmacological Settings., PMID:28253969
Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9., PMID:25963655
MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation., PMID:25816988
In vivo AAV1 transduction with hRheb(S16H) protects hippocampal neurons by BDNF production., PMID:25502903
Induction of GDNF and BDNF by hRheb(S16H) transduction of SNpc neurons: neuroprotective mechanisms of hRheb(S16H) in a model of Parkinson's disease., PMID:24859383
Chromatin remodeling by rosuvastatin normalizes TSC2-/meth cell phenotype through the expression of tuberin., PMID:23426956
Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908., PMID:22356909
Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation., PMID:19864431
Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein., PMID:19299511
Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia., PMID:19258434
RHEB expression in fibroadenomas of the breast., PMID:18324915
Generation and characterization of monoclonal antibodies against tuberous sclerosis complex 2., PMID:17725389
Measuring Ras-family GTP levels in vivo--running hot and cold., PMID:16289967
MCP-1 overexpressed in tuberous sclerosis lesions acts as a paracrine factor for tumor development., PMID:16129702
Novel insulin-elicited phosphoproteins in adipocytes., PMID:15451025
For research use only. Not for human or drug use.
