Catalog No.
PHK46301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human POT1 (Met1-Asp304).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein, POT1
Purification
Purified by antigen affinity column.
Accession
Q9NUX5
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Chronic Lymphocytic Leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing., PMID:38175592
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia., PMID:34518531
The intrinsically disordered N-terminal region of mouse DNA polymerase alpha mediates its interaction with POT1a/b at telomeres., PMID:33711210
Chronic lymphocytic leukemia patients with IGH translocations are characterized by a distinct genetic landscape with prognostic implications., PMID:32720348
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases., PMID:32514122
Pathophysiology of chronic lymphocytic leukemia and human B1 cell development., PMID:31797231
Mechanism of Action of G-Quadruplex-Forming Oligonucleotide Homologous to the Telomere Overhang in Melanoma., PMID:29203363
Profile of POT1 as telomerase shelterin component discriminatesbetween cervical cancer and normal cervical cells., PMID:28425274
Telomere Dysfunction Induced Foci (TIF) Analysis., PMID:27500188
Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle., PMID:27386862
Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy., PMID:27226433
Evidence for multiple forms and modifications of human POT1., PMID:24054699
Altered expression of TPP1 in fibroblast-like synovial cells might be involved in the pathogenesis of rheumatoid arthritis., PMID:21833529
First Report of Pepper mottle virus in Bell Pepper in Taiwan., PMID:30731963
ssDNA fragments induce cell senescence by telomere uncapping., PMID:18778766
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells., PMID:17050546
Alternative splicing of Pot1 (Protection of telomere)-like genes in Arabidopsis thaliana., PMID:15824455
Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins., PMID:15383534
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex., PMID:15231715
Structure and metabolic control of the Yarrowia lipolytica peroxisomal 3-oxoacyl-CoA-thiolase gene., PMID:7916689
For research use only. Not for human or drug use.
