Catalog No.
PHD25101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PRKACA (His40-Lys310).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PRKACA, PKACA, PKA C-alpha, cAMP-dependent protein kinase catalytic subunit alpha
Purification
Purified by antigen affinity column.
Accession
P17612
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
FusionVAC22_01: a phase I clinical trial evaluating a DNAJB1-PRKACA fusion transcript-based peptide vaccine combined with immune checkpoint inhibition for fibrolamellar hepatocellular carcinoma and other tumor entities carrying the oncogenic driver fusion., PMID:38606105
Successful Liver Transplantation of Recurrent Fibrolamellar Carcinoma following Clinical and Pathologic Complete Response to Triple Immunochemotherapy: A Case Report., PMID:35537414
Gene fusions in gastrointestinal tract cancers., PMID:35239225
Histopathological and genetic characterization of aldosterone-producing adenomas with concurrent subclinical cortisol hypersecretion: a case series., PMID:28405879
Double adrenocortical adenomas harboring independent KCNJ5 and PRKACA somatic mutations., PMID:27165862
FGFR1 and FGFR2 in fibrolamellar carcinoma., PMID:26259677
PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling., PMID:24909179
CDC25B acts as a potential target of PRKACA in fertilized mouse eggs., PMID:18633139
Changes in intracellular distribution and activity of protein phosphatase PP1gamma2 and its regulating proteins in spermatozoa lacking AKAP4., PMID:15385410
For research use only. Not for human or drug use.
