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Anti-Human ATF6B Polyclonal Antibody

Catalog #:   PHK45401 Specific References (4) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q99941
Overview

Catalog No.

PHK45401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ATF6B (Ala2-Arg50).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CREBL1, Protein G13, cAMP-responsive element-binding protein-like 1, Activating transcription factor 6 beta, cAMP response element-binding protein-related protein, Cyclic AMP-dependent transcription factor ATF-6 beta, G13, ATF6B, Creb-rp, ATF6-beta, cAMP-dependent transcription factor ATF-6 beta

Purification

Purified by antigen affinity column.

Accession

Q99941

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN-BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with ATF6B antibody (PHK45401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 34 kDa
    Observed MW: 34 kDa
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with ATF6B antibody (PHK45401) at 1 μg/ml.

    Lane 1: HepG2

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 77 kDa
    Observed MW: 77 kDa
  • Immunohistochemical
    Immunohistochemical analysis of human colorectal cancer stained for ATF6B with PHK45401.
References

A gene expression signature in HER2+ breast cancer patients related to neoadjuvant chemotherapy resistance, overall survival, and disease-free survival., PMID:36338974

ATF6β-based fine-tuning of the unfolded protein response enhances therapeutic antibody productivity of Chinese hamster ovary cells., PMID:28165157

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress., PMID:27554968

ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours., PMID:27246726

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human ATF6B Polyclonal Antibody [PHK45401]
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