Catalog No.
PHB24601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human STX11 (Ile93-Lys272).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
STX11, Syntaxin-11
Purification
Purified by antigen affinity column.
Accession
O75558
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect., PMID:38722309
Novel Molecular Therapies and Genetic Landscape in Selected Rare Diseases with Hematologic Manifestations: A Review of the Literature., PMID:36766791
Role of Genetic Polymorphism Present in Macrophage Activation Syndrome Pathway in Post Mortem Biopsies of Patients with COVID-19., PMID:36016321
Neonatal Haemophagocytic Lymphohistiocytosis Associated with Maternal Adult-Onset Still's Disease., PMID:27304999
A possible familial lymphoproliferative disorder in two male siblings of children with recurrent wheezing and lung infections since infancy., PMID:24934116
Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation., PMID:23487749
Clinical aspects, immunologic assessment, and genetic analysis in Taiwanese children with hemophagocytic lymphohistiocytosis., PMID:19057461
Syntaxin-11 is expressed in primary human monocytes/macrophages and acts as a negative regulator of macrophage engulfment of apoptotic cells and IgG-opsonized target cells., PMID:18547321
Severe bacteria-associated hemophagocytic lymphohistiocytosis in an extremely premature infant., PMID:17888050