Catalog No.
PHD19001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human UGT2B7 (Ala285-Asp451).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
UGTB2B9, UDPGTh-2, UDPGT 2B9, UDP-glucuronosyltransferase 2B7, 3,4-catechol estrogen-specific UDPGT, UGT2B7, UDPGT 2B7, UDP-glucuronosyltransferase 2B9
Purification
Purified by antigen affinity column.
Accession
P16662
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Mertansine Inhibits mRNA Expression and Enzyme Activities of Cytochrome P450s and Uridine 5'-Diphospho-Glucuronosyltransferases in Human Hepatocytes and Liver Microsomes., PMID:32131538
Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism., PMID:29203276
Extensive protein-protein interactions involving UDP-glucuronosyltransferase (UGT) 2B7 in human liver microsomes., PMID:24366439
Uridine diphosphate glucuronosyltransferase 2B7 variant p.His268Tyr as a predictor of kidney allograft early acute rejection., PMID:23726609
Human UDP-glucuronosyltransferase expression in insect cells: ratio of active to inactive recombinant proteins and the effects of a C-terminal his-tag on glucuronidation kinetics., PMID:22782802
High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study., PMID:21862974
Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis., PMID:20567810
Interactions between human UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A enzymes., PMID:19475557
Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers., PMID:19439486
Interaction of cytochrome P450 3A4 and UDP-glucuronosyltransferase 2B7: evidence for protein-protein association and possible involvement of CYP3A4 J-helix in the interaction., PMID:19158361
Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling., PMID:18467088
Drug metabolism enzyme expression and activity in primary cultures of human proximal tubular cells., PMID:18055091
Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans., PMID:17132765
High levels of autoantibodies against drug-metabolizing enzymes in SLA/LP-positive AIH-1 sera., PMID:15621574
Coimmunoprecipitation of UDP-glucuronosyltransferase isoforms and cytochrome P450 3A4., PMID:15486048
Human uridine diphosphate-glucuronosyltransferase UGT2B7 conjugates mineralocorticoid and glucocorticoid metabolites., PMID:12746330
Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme., PMID:12435745
Nuclear UDP-glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes., PMID:11883901
Characterization of autoantibodies against uridine-diphosphate glucuronosyltransferase in patients with inflammatory liver diseases., PMID:11343231
Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in the human hepatoma cell line hep G2., PMID:10950852
Immunochemical identification of UGT isoforms in human small bowel and in caco-2 cell monolayers., PMID:10891370
Octamer transcription factor-1 enhances hepatic nuclear factor-1alpha-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter., PMID:10779377
Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine., PMID:10748067
UDP-glucuronosyltransferases in human intestinal mucosa., PMID:9795217
Isolation and characterization of a simian UDP-glucuronosyltransferase UGT2B18 active on 3-hydroxyandrogens., PMID:9480769
For research use only. Not for human or drug use.
