Anti-Human KIF3A Polyclonal Antibody

Catalog No.

PHK44401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KIF3A (Lys16-Ile345).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Microtubule plus end-directed kinesin motor 3A, Kinesin-like protein KIF3A, KIF3A, KIF3

Purification

Purified by antigen affinity column.

Accession

Q9Y496

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Primary cilium participates in radiation-induced bystander effects through TGF-β1 signaling., PMID:38009273

Heterotrimeric Kinesin II is required for flagellar assembly and elongation of nuclear morphology during spermiogenesis in Schmidtea mediterranea., PMID:34090925

Fibroblast Primary Cilia Are Required for Cardiac Fibrosis., PMID:30818997

Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease., PMID:27181777

The growth plate's response to load is partially mediated by mechano-sensing via the chondrocytic primary cilium., PMID:25084815

ERK2-mediated phosphorylation of Par3 regulates neuronal polarization., PMID:23946386

Microtubule modifications and stability are altered by cilia perturbation and in cystic kidney disease., PMID:23124988

Gadkin: A novel link between endosomal vesicles and microtubule tracks., PMID:20798811

Kinesin II is required for cell survival and adherens junction positioning in Drosophila photoreceptors., PMID:20506262

Synaptic input of ON-bipolar cells onto the dopaminergic neurons of the mouse retina., PMID:20394057

Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expression., PMID:20172860

Kaposi's sarcoma-associated herpesvirus ORF45 interacts with kinesin-2 transporting viral capsid-tegument complexes along microtubules., PMID:19282970

Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms., PMID:18084282

RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins., PMID:16043481

Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex., PMID:15728193

Myosin Va and kinesin II motor proteins are concentrated in ribosomal domains (periaxoplasmic ribosomal plaques) of myelinated axons., PMID:15266650

Microtubule-dependent movement of late endocytic vesicles in vitro: requirements for Dynein and Kinesin., PMID:15181154

Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin., PMID:12832475

Expression and partial characterization of kinesin-related proteins in differentiating and adult skeletal muscle., PMID:11102514

Kinesin superfamily protein 3 (KIF3) motor transports fodrin-associating vesicles important for neurite building., PMID:10725338

Photoreceptor localization of the KIF3A and KIF3B subunits of the heterotrimeric microtubule motor kinesin II in vertebrate retina., PMID:10548469

Characterization of the KIF3C neural kinesin-like motor from mouse., PMID:9450952

Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B., PMID:8710890

Localization of kinesin superfamily proteins to the connecting cilium of fish photoreceptors., PMID:8718680

KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport., PMID:7559760

KIF2 is a new microtubule-based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain or KIF3A/B., PMID:7535303

KIF3A is a new microtubule-based anterograde motor in the nerve axon., PMID:7515068

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