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Anti-Human APEX1 Polyclonal Antibody

Catalog #:   PHD74801 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P27695
Overview

Catalog No.

PHD74801

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human APEX1 (Thr61-Leu318).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

APX, APE1, APEX nuclease, APEN, Redox factor-1, APE-1, REF1, APEX, APE, Apurinic-apyrimidinic endonuclease 1, HAP1, AP endonuclease 1, APEX1, DNA-(apurinic or apyrimidinic site) endonuclease, REF-1

Purification

Purified by antigen affinity column.

Accession

P27695

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with APEX1 antibody (PHD74801) at 1μg/ml.

    Lane 1: HepG2 cell lysate
    Lane 2: Raji cell lysate
    Lane 3: 293T cell lysate
    Lane 4: Mouse spleen lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 36 kDa
    Observed MW: 36 kDa
  • Immunohistochemical
    Immunohistochemical analysis of human breast tissue stained for APEX1 with PHD74801.
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with APEX1 antibody (PHD74801) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 32 kDa
    Observed MW: 32 kDa
References

Development of Thyrotoxicosis With Positive TSH Receptor Antibody and Transition to Hypothyroidism in a Patient With Unresectable Hepatocellular Carcinoma During Combined Atezolizumab and Bevacizumab Therapy: A Case Report and Review of the Literature., PMID:40518311

Zinc-Induced Copper Deficiency Myeloneuropathy Masquerading as Paraneoplastic Syndrome: A Case Report., PMID:40416147

Multi-epitope microsphere vaccine modified immunological efficacy against LMBV in largemouth bass (Micropterus salmoides)., PMID:40279807

[A case of heparin-induced thrombocytopenia (HIT) developing into seizure and respiratory arrest caused by continuous intravenous heparin infusion for multiple cerebral infarcts]., PMID:40128928

Proteolysis-Based Biomarker Repertoire of the Neurofilament Proteome., PMID:40066701

Follow-Up of SARS-CoV-2 Antibody Levels in Belgian Nursing Home Residents and Staff Two, Four and Six Months after Primary Course BNT162b2 Vaccination., PMID:39204074

Solitary fibrous tumor of thyroid: Case report., PMID:39138014

Return on investment in science: twenty years of European Commission funded research in Alzheimer's dementia, breast cancer and prostate cancer., PMID:38880873

Prevalence of Acute Hepatitis E Virus Infections in Swiss Blood Donors 2018-2020., PMID:38793625

Hepatotoxicity as dose-limiting toxicity of the combination of bosutinib and atezolizumab in patients with chronic myeloid leukemia. Results of the ZEROLMC study., PMID:38568260

Primary Mediastinal Gray Zone Lymphoma in an Immunocompetent Young Adult., PMID:37915147

MODY5 and Serous Ovarian Carcinoma in 17q12 Recurrent Deletion Syndrome., PMID:37520763

Algorithm for tracking peaks amongst numerous datasets in comprehensive two-dimensional chromatography to enhance data analysis and interpretation., PMID:37487299

Characterization of Early Gonadal Differentiation and Induction of Sex Reversal in the Rock Bream Oplegnathus fasciatus., PMID:37162621

Trough Concentration Response in Infliximab and Adalimumab Treated Children With Inflammatory Bowel Disease Following Treatment Adjustment: A Pharmacokinetic Model., PMID:37083732

In Vitro Anti-Venom Potentials of Aqueous Extract and Oils of Toona ciliata M. Roem against Cobra Venom and Chemical Constituents of Oils., PMID:37049851

Identification of non-neutralizing anti-factor X autoantibodies in three Japanese cases of autoimmune acquired factor X deficiency., PMID:36478471

A Case of Diffuse Large B-Cell Lymphoma Complicated by Helicobacter Pylori-Negative Russell Body Gastritis., PMID:36412027

Do Bacteria Provide an Alternative to Cancer Treatment and What Role Does Lactic Acid Bacteria Play?, PMID:36144335

Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system., PMID:36131342

Assessment of neutralizing antibody responses after natural SARS-CoV-2 infection and vaccination in congolese individuals., PMID:35831798

A man in his fifties with recurrent urticaria, fever and joint pain., PMID:35239264

Waldenstrom Macroglobulinemia/Lymphoplasmacytic Lymphoma Associated with Nephrotic Syndrome during Hemodialysis, Treated Successfully with Tirabrutinib., PMID:35110483

Short-term effectiveness of COVID-19 vaccines in immunocompromised patients: A systematic literature review and meta-analysis., PMID:34982962

Advances in therapeutic targets-related study on systemic lupus erythematosus., PMID:34911862

Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium., PMID:34853321

Vaccination in children with inherited bleeding disorders: Does the use of plasma an d factor affect the response to the vaccine: An institutional registry., PMID:34799967

Automated subcortical volume estimation from 2D MRI in epilepsy and implications for clinical trials., PMID:34661698

Experimental infection of ostriches with H7N1 low pathogenic and H5N8 clade 2.3.4.4B highly pathogenic influenza A viruses., PMID:34656859

A rheumatoid arthritis patient with delivery who started certolizumab pegol and tacrolimus during pregnancy., PMID:34477867

Double-Barrel Shotgun: Probiotic Lactic Acid Bacteria with Antiviral Properties Modified to Serve as Vaccines., PMID:34442644

Cell contact guidance via sensing anisotropy of network mechanical resistance., PMID:34266950

Systemic administration of polymersomal oncolytic peptide LTX-315 combining with CpG adjuvant and anti-PD-1 antibody boosts immunotherapy of melanoma., PMID:34174350

[A Case of Neuromyelitis Optica Spectrum Disorder Who Relapsed Under Oral Corticosteroid Treatment with Multiple Cerebrospinal Lesions and Severe Neurological Deficits]., PMID:34092770

The influence of the antithymocyte globulin dose on clinical outcomes of patients undergoing kidney retransplantation., PMID:33979389

Primary Central Nervous System Vasculitis as an Unusual Cause of Intracerebral Hemorrhage: A Case Report., PMID:33854857

The role of protein hydrolysates in prolonging viability and enhancing antibody production of CHO cells., PMID:33796891

Molecular Dynamics-Guided Design of a Functional Protein-ATRP Conjugate That Eliminates Protein-Protein Interactions., PMID:33784809

[A Case of Thyroid Dysfunction and Isolated Adrenocorticotropin Deficiency after Nivolumab Therapy for Malignant Melanoma]., PMID:33678791

RFX1-mediated CCN3 induction that may support chondrocyte survival under starved conditions., PMID:33655492

Double ion-exchange reaction-based photoelectrochemical immunoassay for sensitive detection of prostate-specific antigen., PMID:33551059

Establishment and verification of an osteoporosis risk model in patients with rheumatoid arthritis: a valuable new model., PMID:33394305

Disruption of Zika Virus xrRNA1-Dependent sfRNA1 Production Results in Tissue-Specific Attenuated Viral Replication., PMID:33080971

Insights into the evolution of IG genes in Amphibians and reptiles., PMID:32949685

Rapidly progressive glomerulonephritis after introduction of certolizumab pegol: a case report., PMID:32687015

Colorectal cancer is associated with increased circulating lipopolysaccharide, inflammation and hypercoagulability., PMID:32472080

Methotrexate-associated Hodgkin Lymphoma in a Patient with Rheumatoid Arthritis Successfully Treated with Brentuximab Vedotin in Combination with Doxorubicin, Vinblastine, and Dacarbazine (BV+AVD)., PMID:32461524

Impact of vaccination on measles, mumps, and rubella antibody titers in Japanese healthcare workers: An observational study., PMID:32208432

Evaluation of matrix effects and prolonged storage on Trypanosoma cruzi serology in blood donor specimens., PMID:32163175

Label-free quantitative identification of abnormally ubiquitinated proteins as useful biomarkers for human lung squamous cell carcinomas., PMID:32140187

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human APEX1 Polyclonal Antibody [PHD74801]
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