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Anti-Human NFATC3 Polyclonal Antibody

Catalog #:   PHG35601 Specific References (20) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q12968
Overview

Catalog No.

PHG35601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NFATC3 (Gln430-Lys703).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

NF-AT4c, Nuclear factor of activated T-cells, cytoplasmic 3, NFATx, NFAT4, NFATC3, NF-AT4, T-cell transcription factor NFAT4, NFATc3, NF-ATc3

Purification

Purified by antigen affinity column.

Accession

Q12968

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN-BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with NFATC3 antibody (PHG35601) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 33 kDa
    Observed MW: 33 kDa
References

Overcoming PD-1 Inhibitor Resistance with a Monoclonal Antibody to Secreted Frizzled-Related Protein 2 in Metastatic Osteosarcoma., PMID:34070758

Serum microRNAs as Tool to Predict Early Response to Benralizumab in Severe Eosinophilic Asthma., PMID:33525548

Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid-induced monocyte trafficking., PMID:28724635

Cardiomyocyte Hypertrophy in Arrhythmogenic Cardiomyopathy., PMID:28183531

Expression of Signaling Molecules in Progressive Multifocal Leukoencephalopathy., PMID:26531763

Tumor endothelial expression of P-glycoprotein upon microvesicular transfer of TrpC5 derived from adriamycin-resistant breast cancer cells., PMID:24582564

FGF2 activates TRPC and Ca(2+) signaling leading to satellite cell activation., PMID:24575047

NFATc2 (NFAT1) assists BCR-mediated anergy in anti-insulin B cells., PMID:24507801

Calcium efflux activity of plasma membrane Ca2+ ATPase-4 (PMCA4) mediates cell cycle progression in vascular smooth muscle cells., PMID:24448801

A novel monoclonal antibody to secreted frizzled-related protein 2 inhibits tumor growth., PMID:23604067

CXCL13 activation of c-Myc induces RANK ligand expression in stromal/preosteoblast cells in the oral squamous cell carcinoma tumor-bone microenvironment., PMID:22330139

Nuclear presence of nuclear factor of activated T cells (NFAT) c3 and c4 is required for Toll-like receptor-activated innate inflammatory response of monocytes/macrophages., PMID:21726630

The role of calcineurin/NFAT in SFRP2 induced angiogenesis--a rationale for breast cancer treatment with the calcineurin inhibitor tacrolimus., PMID:21673995

Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes., PMID:21474694

A novel function of CXCL13 to stimulate RANK ligand expression in oral squamous cell carcinoma cells., PMID:19671684

Glycogen synthase kinase 3 suppresses myogenic differentiation through negative regulation of NFATc3., PMID:17977834

FGF18 represses noggin expression and is induced by calcineurin., PMID:15252029

Selective expression of nuclear factor of activated T cells 2/c1 in human basophils: evidence for involvement in IgE-mediated IL-4 generation., PMID:11897999

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development., PMID:9846484

Expression of NFAT-family proteins in normal human T cells., PMID:9111316

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human NFATC3 Polyclonal Antibody [PHG35601]
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