Catalog No.
PHK41301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human IGF2BP1 (Val194-Asn369).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
VICKZ family member 1, Zipcode-binding protein 1, IGF2BP1, VICKZ1, Coding region determinant-binding protein, IMP1, IMP-1, ZBP1, IGF-II mRNA-binding protein 1, CRDBP, Insulin-like growth factor 2 mRNA-binding protein 1, ZBP-1, CRD-BP, IGF2 mRNA-binding protein 1
Purification
Purified by antigen affinity column.
Accession
Q9NZI8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Lactylation of HDAC1 Confers Resistance to Ferroptosis in Colorectal Cancer., PMID:39888307
Identification and classification of abundant RNA-binding proteins in the mouse lens and interactions of Carhsp1, Igf2bp1/ZBP1, and Ybx1 with crystallin and β-actin mRNAs., PMID:39829794
Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D., PMID:39809921
FGF19/FGFR4 signaling contributes to hepatocellular carcinoma survival and immune escape by regulating IGF2BP1-mediated expression of PD-L1., PMID:38048735
Neural Stem Cell Extracellular Vesicles Carrying YBX1 Inhibited Neuronal Pyroptosis Through Increasing m6A-modified GPR30 Stability and Expression in Ischemic Stroke., PMID:37966628
HNRNPL induced circFAM13B increased bladder cancer immunotherapy sensitivity via inhibiting glycolysis through IGF2BP1/PKM2 pathway., PMID:36747239
m6A methylation regulators as predictors for treatment of advanced urothelial carcinoma with anti-PDL1 agent., PMID:36189296
Enhanced immunoprecipitation techniques for the identification of RNA-binding protein partners: IGF2BP1 interactions in mammary epithelial cells., PMID:35104504
RNA Demethylase FTO Mediated RNA m6A Modification Is Involved in Maintaining Maternal-Fetal Interface in Spontaneous Abortion., PMID:34350169
CircPTPRA blocks the recognition of RNA N6-methyladenosine through interacting with IGF2BP1 to suppress bladder cancer progression., PMID:33853613
Epitranscriptomics in liver disease: Basic concepts and therapeutic potential., PMID:32330603
Antibody Responses to Cancer Antigens Identify Patients with a Poor Prognosis among HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Patients., PMID:31444248
The Prevalence of Cancer-Associated Autoantibodies in Patients with Gastric Cancer and Progressive Grades of Premalignant Lesions., PMID:28768706
Anti-cytoplasmic Autoantibodies in Hodgkin's Lymphoma., PMID:28164609
Signaling pathways controlling activity-dependent local translation of BDNF and their localization in dendritic arbors., PMID:27270670
XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A., PMID:25878333
Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor Cells., PMID:25861986
Detection of autoantibodies to multiple tumor-associated antigens (TAAs) in the immunodiagnosis of breast cancer., PMID:25355596
IGF2BP1: a novel IGH translocation partner in B acute lymphoblastic leukemia., PMID:25195122
The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer., PMID:25068994
Humoral autoimmune responses to insulin-like growth factor II mRNA-binding proteins IMP1 and p62/IMP2 in ovarian cancer., PMID:24872956
IGH@ translocations co-exist with other primary rearrangements in B-cell precursor acute lymphoblastic leukemia., PMID:24816234
VICKZ2 protein expression in ovarian serous carcinoma effusions is associated with poor survival., PMID:24814803
Autoantibody detection to tumor-associated antigens of P53, IMP1, P16, cyclin B1, P62, C-myc, Survivn, and Koc for the screening of high-risk subjects and early detection of esophageal squamous cell carcinoma., PMID:24147952
Isolation of RNP granules., PMID:21125496
Evaluation of serum autoantibody levels in the diagnosis of ovarian endometrioma., PMID:20872572
Phosphorylation of zipcode binding protein 1 is required for brain-derived neurotrophic factor signaling of local beta-actin synthesis and growth cone turning., PMID:20631164
Evaluation of tumour-associated antigen (TAA) miniarray in immunodiagnosis of colon cancer., PMID:19140877
Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs., PMID:19029303
Targeted knockdown of the RNA-binding protein CRD-BP promotes cell proliferation via an insulin-like growth factor II-dependent pathway in human K562 leukemia cells., PMID:15355996
Autoantibodies to IGF-II mRNA binding protein p62 and overexpression of p62 in human hepatocellular carcinoma., PMID:12849008