Catalog No.
PHE23202
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HSPA9/Mortalin/GRP75 (Lys52-Asp431).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
mt-HSP70, HSPA9B, MOT, Peptide-binding protein 74, Stress-70 protein, mitochondrial, PBP74, GRP-75, Mortalin, Heat shock 70 kDa protein 9, GRP75, 75 kDa glucose-regulated protein, HSPA9
Purification
Purified by antigen affinity column.
Accession
P38646
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Quantitative proteomics reveals cellular responses to individual mAb expression and tunicamycin in CHO cells., PMID:38896138
HSP70s in Breast Cancer: Promoters of Tumorigenesis and Potential Targets/Tools for Therapy., PMID:34943954
Expressions of HSPA1L and HSPA9 are associated with poor sperm quality of low-motility spermatozoa in fertile men., PMID:34796524
Toxoplasma gondii association with host mitochondria requires key mitochondrial protein import machinery., PMID:33723040
Mortalin peptides exert antitumor activities and act as adjuvants to antibody-mediated complement-dependent cytotoxicity., PMID:32700755
Overexpression of PGC-1α influences the mitochondrial unfolded protein response (mtUPR) induced by MPP+ in human SH-SY5Y neuroblastoma cells., PMID:32591623
Express ELISA for detection of mortalin., PMID:31502469
Production of a Mouse Monoclonal Antibody Against Mortalin by Whole Cell Immunization., PMID:28719245
Mortalin expression in pancreatic cancer and its clinical and prognostic significance., PMID:28412209
Characterization of MAGEG2 with testis-specific expression in mice., PMID:27852984
Identification of heat shock protein A9 as a Tembusu virus binding protein on DF-1 cells., PMID:27693918
Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis., PMID:26717306
Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways., PMID:26717040
Functional significance of point mutations in stress chaperone mortalin and their relevance to Parkinson disease., PMID:25645922
Integrative quantitative proteomics unveils proteostasis imbalance in human hepatocellular carcinoma developed on nonfibrotic livers., PMID:25225353
Hep88 mAb-initiated paraptosis-like PCD pathway in hepatocellular carcinoma cell line through the binding of mortalin (HSPA9) and alpha-enolase., PMID:25788858
mot-2-Mediated cross talk between nuclear factor-B and p53 is involved in arsenite-induced tumorigenesis of human embryo lung fibroblast cells., PMID:20199942
Mortalin imaging in normal and cancer cells with quantum dot immuno-conjugates., PMID:14728808
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75., PMID:11959102
Asymmetric segregation of mitochondria and mortalin correlates with the multi-lineage potential of inner ear sensory cell progenitors in vitro., PMID:11850063
Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75., PMID:10944461
NIH 3T3 cells malignantly transformed by mot-2 show inactivation and cytoplasmic sequestration of the p53 protein., PMID:10628835
Induction of novel Grp75 isoforms by 2-deoxyglucose in human and murine fibroblasts., PMID:9570370
Monoclonal development of squamous cell carcinomas from polyclonal papillary or nodular hyperplasias in the forestomach of C3H/HeN<-->BALB/c chimeric mice treated with N-methyl-N-nitrosourea or diethylnitrosamine., PMID:8681457
Primary monoclonal and secondary polyclonal growth of colon neoplastic lesions in C3H/HeN<-->BALB/c chimeric mice treated with 1,2-dimethylhydrazine immunohistochemical detection of C3H strain-specific antigen and simple sequence length polymorphism analysis of DNA., PMID:8603817
PBP74, a new member of the mammalian 70-kDa heat shock protein family, is a mitochondrial protein., PMID:7865888
Antigenic protein specific for C3H strain mouse is a mitochondrial stress-70 protein., PMID:7692847
Differential subcellular distribution of mortalin in mortal and immortal mouse and human fibroblasts., PMID:8344392
Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype., PMID:8454632
For research use only. Not for human or drug use.
