Catalog No.
PHF61201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PPP2CA (Met1-Leu309).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Replication protein C, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, RP-C, PP2A-alpha, PPP2CA
Purification
Purified by antigen affinity column.
Accession
P67775
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Analysing transcriptomic signatures and identifying potential genes for the protective effect of inactivated COVID-19 vaccines., PMID:37096063
Proteomic analysis of host cellular proteins co-immunoprecipitated with duck enteritis virus gC., PMID:34091090
PP2Acα inhibits PFKFB2-induced glycolysis to promote termination of liver regeneration., PMID:32192773
Antibodies recognizing the C terminus of PP2A catalytic subunit are unsuitable for evaluating PP2A activity and holoenzyme composition., PMID:31992581
Measurement of Microcystin and Nodularin Activity in Human Urine by Immunocapture-Protein Phosphatase 2A Assay., PMID:31847123
Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium., PMID:29500169
Passive immunization targeting the N-terminal region of phosphorylated tau (residues 68-71) improves spatial memory in okadaic acid induced tauopathy model rats., PMID:27998769
Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair., PMID:25245035
Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720., PMID:24460909
Over one-third of African-American MGUS and multiple myeloma patients are carriers of hyperphosphorylated paratarg-7, an autosomal dominantly inherited risk factor for MGUS/MM., PMID:24443359
NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function., PMID:23921553
Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups., PMID:21590681
BEX2 regulates mitochondrial apoptosis and G1 cell cycle in breast cancer., PMID:19711341
Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1., PMID:19622840
Cantharidin-induced mitotic arrest is associated with the formation of aberrant mitotic spindles and lagging chromosomes resulting, in part, from the suppression of PP2Aalpha., PMID:17121919
For research use only. Not for human or drug use.
