Catalog No.
PHK40201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PHB2 (Ser39-Arg191).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Repressor of estrogen receptor activity, B-cell receptor-associated protein BAP37, D-prohibitin, BAP, Prohibitin-2, PHB2, REA
Purification
Purified by antigen affinity column.
Accession
Q99623
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Treatment of Reactive Arthritis with Biological Agents., PMID:39312088
PHB2 inhibits WSSV replication by promoting the nuclear translocation of STAT., PMID:38479567
Nur77 increases mitophagy and decreases aggregation of α-synuclein by modulating the p-c-Abl/p-PHB2 Y121 in α-synuclein PFF SH-SY5Y cells and mice., PMID:38422699
Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids., PMID:38332916
Myeloid-derived grancalcin instigates obesity-induced insulin resistance and metabolic inflammation in male mice., PMID:38167327
Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment., PMID:37978291
Identification of PHB2 as a Potential Biomarker of Luminal A Breast Cancer Cells Using a Cell-Specific Aptamer., PMID:36346944
Mechanical detection of interactions between proteins related to intermediate filament and transcriptional regulation in living cells., PMID:35964349
INACTIVATED COVID-19 VACCINE CAN INDUCE REACTIVE POLYARTHRITIS IN OLDER PATIENTS: REPORT OF TWO CASES., PMID:34749331
Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer., PMID:34185411
THE PRINCIPLE OF COMBINED PREOPERATIVE DIAGNOSIS OF THYROID TUMORS., PMID:33813463
Diagnostic value of serum connective tissue growth factor in rheumatoid arthritis., PMID:33389316
SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2., PMID:32826957
Reactive arthritis after COVID-19 infection., PMID:32763956
Molecular characterization of prohibitins and their differential responses to WSSV infection in hemocyte subpopulations of Fenneropenaeus chinensis., PMID:32717325
Prevalence of anti-cyclic citrullinated peptide antibodies in patients with spondyloarthritis: A retrospective study., PMID:32340503
Chlamydia-induced reactive arthritis diagnosed during gout flares: A case report and cumulative effect of inflammatory cytokines on chronic arthritis., PMID:31577714
CTHRC1: A New Candidate Biomarker for Improved Rheumatoid Arthritis Diagnosis., PMID:31249576
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Advances in the treatment of uveitis in patients with spondyloarthritis - is it the time for biologic therapy?, PMID:30206554
Shortening the washout to 4 weeks when switching from natalizumab to fingolimod and risk of disease reactivation in multiple sclerosis., PMID:30014876
TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics., PMID:29715546
A mouse model with age-dependent immune response and immune-tolerance for HBV infection., PMID:29306503
Reactive Arthritis Caused by Yersinia enterocolitica Enteritis., PMID:28502944
Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes., PMID:28187984
Do IgA antibodies to Chlamydia trachomatis have protective role in humoral immunity: a study in reactive arthritis patients., PMID:26482506
Identification of a panel of complex autoantigens (LGALS3, PHB2, MUC1, and GK2) in combination with CA15-3 for the diagnosis of early-stage breast cancer., PMID:26289852
A multiparametric serum marker panel as a complementary test to mammography for the diagnosis of node-negative early-stage breast cancer and DCIS in young women., PMID:24957886
Diagnosis of Chlamydia trachomatis in patients with reactive arthritis and undifferentiated spondyloarthropathy., PMID:24820470
Prohibitin 2 represents a novel nuclear AKT substrate during all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells., PMID:24522204
Role of 30 kDa antigen of enteric bacterial pathogens as a possible arthritogenic factor in post-dysenteric reactive arthritis., PMID:24152499
A role for prohibitin in mast cell activation: location matters., PMID:24023253
Activation of human natural killer cells by the novel innate immune modulator recombinant Eimeria antigen., PMID:23639554
Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides., PMID:23592052
The role of monocytes and SLC11A1 polymorphisms in the pathogenesis of Chlamydia-induced reactive arthritis., PMID:23244274
Alteration in localization of steroid hormone receptors and coregulatory proteins in follicles from cows with induced ovarian follicular cysts., PMID:23081895
Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early-stage breast cancers., PMID:22886747
Signalling profiles of circulating leucocytes in patients recovered from reactive arthritis., PMID:22651550
Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation., PMID:22212092
Reactive arthritis in a population exposed to an extensive waterborne gastroenteritis outbreak after sewage contamination in Pirkanmaa, Finland., PMID:21679096
Utility of the peripheral blood basophil histamine release test in the diagnosis of hen's egg, cow's milk, and wheat allergy in children., PMID:21646803
Evidence of cellular immune response to outer membrane protein of Salmonella typhimurium in patients with enthesitis-related arthritis subtype of juvenile idiopathic arthritis., PMID:21041273
Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein., PMID:19906925
Insulin induced phosphorylation of prohibitin at tyrosine 114 recruits Shp1., PMID:19497338
Similarity between chronic reactive arthritis and ankylosing spondylitis.A 32-35-year follow-up study., PMID:19473576
Prevalence of antibodies against Chlamydia trachomatis and incidence of C. trachomatis-induced reactive arthritis in an early arthritis series in Finland in 2000., PMID:19296404
Detection and frequency of Chlamydia trachomatis DNA in synovial samples from Tunisian patients with reactive arthritis and undifferentiated oligoarthritis., PMID:19159429
Monitoring therapy in canine malignant lymphoma and leukemia with serum thymidine kinase 1 activity--evaluation of a new, fully automated non-radiometric assay., PMID:19148486
The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma., PMID:18795076
[Some proteins of acute phase of inflammation in differential diagnostics of rheumatoid arthritis]., PMID:18720714
For research use only. Not for human or drug use.
