Anti-Human PRDX1 Polyclonal Antibody

Catalog No.

PHG10501

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PRDX1 (Lys16-Lys199).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Thioredoxin-dependent peroxide reductase 2, PAGB, Thioredoxin peroxidase 2, Proliferation-associated gene protein, Thioredoxin-dependent peroxiredoxin 1, PAG, PAGA, Peroxiredoxin-1, Natural killer cell-enhancing factor A, TDPX2, NKEF-A, PRDX1

Purification

Purified by antigen affinity column.

Accession

Q06830

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Discovery of indole analogue Tc3 as a potent pyroptosis inducer and identification of its combination strategy against hepatic carcinoma., PMID:39816682

Extracellular Prdx1 mediates bacterial infection and inflammatory bone diseases., PMID:37797684

Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-κB signaling., PMID:37164261

Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto's Thyroiditis., PMID:33916948

The prognostic value of JUNB-positive CTCs in metastatic breast cancer: from bioinformatics to phenotypic characterization., PMID:31370904

Tumor cells induce LAMP2a expression in tumor-associated macrophage for cancer progression., PMID:30711520

Multiple reaction monitoring targeted LC-MS analysis of potential cell death marker proteins for increased bioprocess control., PMID:29607450

Stimulatory function of peroxiredoxin 1 in activating adaptive humoral immunity in a zebrafish model., PMID:29518406

Peroxiredoxin I expression in epithelial cells of buccal mucosa from patients exposed to panoramic X-rays: influence of the age., PMID:29063384

Upregulation of thioredoxin-1 in activated human NK cells confers increased tolerance to oxidative stress., PMID:28224212

Peroxiredoxin 1 induces inflammatory cytokine response and predicts outcome of cardiogenic shock patients necessitating extracorporeal membrane oxygenation: an observational cohort study and translational approach., PMID:27142532

Reactive oxygen species mediate oxaliplatin-induced epithelial-mesenchymal transition and invasive potential in colon cancer., PMID:26733168

Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells., PMID:26094816

Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer., PMID:25011585

Cancer-derived immunoglobulin G promotes tumor cell growth and proliferation through inducing production of reactive oxygen species., PMID:24309932

Peroxiredoxin 1 is a tumor-associated antigen in esophageal squamous cell carcinoma., PMID:24009050

Stromal response to prostate cancer: nanotechnology-based detection of thioredoxin-interacting protein partners distinguishes prostate cancer associated stroma from that of benign prostatic hyperplasia., PMID:23762225

Expression of peroxiredoxins I and IV in multiple myeloma: association with immunoglobulin accumulation., PMID:23737084

Role of proinflammatory CD68(+) mannose receptor(-) macrophages in peroxiredoxin-1 expression and in abdominal aortic aneurysms in humans., PMID:23241402

Cross-reactive antibodies to target proteins are dependent upon oligomannose glycosylated epitopes in HTLV-1 associated neurological disease., PMID:22392044

Using proteomic approach to identify tumor-associated proteins as biomarkers in human esophageal squamous cell carcinoma., PMID:21517111

Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer., PMID:21165559

Proteomics characterization of cell model with renal fibrosis phenotype: osmotic stress as fibrosis triggering factor., PMID:21118732

Proteomic analysis in cyclosporin A-induced overgrowth of human gingival fibroblasts., PMID:19652395

Production and radioimmunoimaging of novel fully human phage display recombinant antibodies and growth inhibition of lung adenocarcinoma cell line overexpressing Prx I., PMID:19556853

Novel protective mechanism against irreversible hyperoxidation of peroxiredoxin: Nalpha-terminal acetylation of human peroxiredoxin II., PMID:19286652

Hepatocytes proteomic alteration and seroproteome analysis of HBV-transgenic mice., PMID:19053081

Post-translational glycosylation of target proteins implicate molecular mimicry in the pathogenesis of HTLV-1 associated neurological disease., PMID:18793806

Peroxiredoxin I is differentially expressed in multiple myelomas and in plasmablastic lymphomas., PMID:18565146

Increase in expression levels and resistance to sulfhydryl oxidation of peroxiredoxin isoforms in amyloid beta-resistant nerve cells., PMID:17761673

Immunohistochemical localization of 2-Cys peroxiredoxins in human ciliary body., PMID:17707450

Histological recovery of the hepatocytes is based on the redox system upregulation in the animal models of mutant superoxide dismutase (SOD)1-linked amyotrophic lateral sclerosis., PMID:16598672

Comparative proteomic analysis identifies protein disulfide isomerase and peroxiredoxin 1 as new players involved in embryonic interdigital cell death., PMID:15858817

Expression of peroxiredoxins in bovine oocytes and embryos produced in vitro., PMID:15349835

Document Download

Anti-Human PRDX1 Polyclonal Antibody.pdf