Catalog No.
PHK39801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TNFAIP8L2 (Met1-Leu184).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TNF alpha-induced protein 8-like protein 2, Tumor necrosis factor alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2, Inflammation factor protein 20, TIPE2, TNFAIP8L2
Purification
Purified by antigen affinity column.
Accession
Q6P589
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation., PMID:34702807
TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis., PMID:31662347
TIPE2 in dendritic cells inhibits the induction of pTregs in the gut mucosa., PMID:30638932
Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells., PMID:30637920
Hepatitis C virus promotes hepatocellular carcinogenesis by targeting TIPE2, a new regulator of DNA damage response., PMID:27696294
Anti-inflammatory TIPE2 inhibits angiogenic VEGF in retinal pigment epithelium., PMID:27043859
The pro-apoptotic effects of TIPE2 on AA rat fibroblast-like synoviocytes via regulation of the DR5-caspase-NF-κB pathway in vitro., PMID:27013892
The expression and significance of TIPE2 in peripheral blood mononuclear cells from asthmatic children., PMID:24107080
TIPE2, a novel biomarker for clinical chronic kidney allograft rejection., PMID:23009108
The unique expression profile of human TIPE2 suggests new functions beyond its role in immune regulation., PMID:21459448
Tissue-specific expression of TIPE2 provides insights into its function., PMID:20663561