Catalog No.
PHE68401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CEBPA (Asn281-Ala358).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
C/EBP alpha, CCAAT/enhancer-binding protein alpha, CEBPA, CEBP
Purification
Purified by antigen affinity column.
Accession
P49715
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
TIMEPOINT, a phase 1 study combining MTL-CEBPA with pembrolizumab, supports the immunomodulatory effect of MTL-CEBPA in solid tumors., PMID:40168999
Tumor-derived CCL15 regulates RNA m6A methylation in cancer-associated fibroblasts to promote hepatocellular carcinoma growth., PMID:39734010
7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice., PMID:38909257
The lncRNA expression profile signature of leukemia stem cells is altered upon PI3K/mTOR inhibition: an in vitro and in silico study., PMID:37470414
A clinicopathological experience in acute myeloid leukemia: Effects of clinical data and status of FLT3, CEBPA and NPM1 on prognosis., PMID:35900493
CEBPA mutants down-regulate AML cell susceptibility to NK-mediated lysis by disruption of the expression of NKG2D ligands, which can be restored by LSD1 inhibition., PMID:35003895
Dysregulation of PI3K and Hippo signaling pathways synergistically induces chronic pancreatitis via CTGF upregulation., PMID:34032634
Anacardic Acid Suppresses Adipogenesis Through Inhibition of the Hsp90/Akt Signaling Pathway in 3T3-L1 Preadipocytes., PMID:34009020
Molecular classification and prognosis in younger adults with acute myeloid leukemia and intermediate-risk cytogenetics treated or not by gemtuzumab ozogamycin: Final results of the GOELAMS/FILO acute myeloid leukemia 2006-intermediate-risk trial., PMID:33765335
Outcomes following hematopoietic stem cell transplantation in patients treated with standard chemotherapy with or without gemtuzumab ozogamicin for acute myeloid leukemia., PMID:33564120
The predicting role of circulating tumor DNA landscape in gastric cancer patients treated with immune checkpoint inhibitors., PMID:33126883
Single-cell RNA-Seq of follicular lymphoma reveals malignant B-cell types and coexpression of T-cell immune checkpoints., PMID:30591526
[AML in Adults - An Update on Diagnosis, Risk Classification and Therapy]., PMID:30199909
Inhibition of Casein Kinase 2 Disrupts Differentiation of Myeloid Cells in Cancer and Enhances the Efficacy of Immunotherapy in Mice., PMID:30139814
Orchestration of B lymphoid cells and their inner myeloid by Bach., PMID:26894991
Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators., PMID:26019273
Transcriptome analysis of medaka following epinecidin-1 and TH1-5 treatment of NNV infection., PMID:25449377
CCAAT/enhancer-binding protein α negatively regulates IFN-γ expression in T cells., PMID:25398328
Hematopoiesis in the equine fetal liver suggests immune preparedness., PMID:25179685
IGH@ translocations co-exist with other primary rearrangements in B-cell precursor acute lymphoblastic leukemia., PMID:24816234
Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: results of the ALFA-0701 trial., PMID:24659740
Transcription onset of genes critical in liver carcinogenesis is epigenetically regulated by methylated DNA-binding protein MBD2., PMID:23955541
C/EBPα and DEK coordinately regulate myeloid differentiation., PMID:22474248
Evaluation of prognostic factors in AML. Preface., PMID:22127310
Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells., PMID:21791434
CD40L induces inflammation and adipogenesis in adipose cells--a potential link between metabolic and cardiovascular disease., PMID:20174757
Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen., PMID:18212247
[Acute myeloid leukemia]., PMID:18079616
Fat depot-related differences in gene expression, adiponectin secretion, and insulin action and signalling in human adipocytes differentiated in vitro from precursor stromal cells., PMID:17960360
Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)., PMID:17170124
Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia., PMID:16873674
DNA mimics a self-protein that may be a target for some anti-DNA antibodies in systemic lupus erythematosus., PMID:7836777
For research use only. Not for human or drug use.
