Anti-Human SLC4A4 Polyclonal Antibody

Catalog No.

PHK39401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLC4A4 (Pro106-Ser233).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Na(+)/HCO3(-) cotransporter, SLC4A4, NBC1, NBCE1, NBC, Sodium bicarbonate cotransporter, Solute carrier family 4 member 4, kNBC1, Electrogenic sodium bicarbonate cotransporter 1

Purification

Purified by antigen affinity column.

Accession

Q9Y6R1

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Construction of molecular subgroups of ulcerative colitis., PMID:37843347

Revisiting the Role of Ser982 Phosphorylation in Stoichiometry Shift of the Electrogenic Na+/qHCO3- Cotransporter NBCe1., PMID:34884619

Calcineurin/P38MAPK/HSP27-dependent pathways are involved in the attenuation of postischemic mitochondrial injury afforded by sodium bicarbonate co-transporter (NBCe1) inhibition., PMID:30615862

Expression of the B splice variant of NBCe1 (SLC4A4) in the mouse kidney., PMID:29631353

Na+/HCO3- cotransporter is expressed on β and α cells during rat pancreatic development., PMID:27920473

The cardiac electrogenic sodium/bicarbonate cotransporter (NBCe1) is activated by aldosterone through the G protein-coupled receptor 30 (GPR 30)., PMID:27249584

The sodium-bicarbonate cotransporter NBCe2 (slc4a5) expressed in human renal proximal tubules shows increased apical expression under high-salt conditions., PMID:26447209

Role of Sodium Bicarbonate Cotransporters in Intracellular pH Regulation and Their Regulatory Mechanisms in Human Submandibular Glands., PMID:26375462

NBCe1 (SLC4A4) a potential pH regulator in enamel organ cells during enamel development in the mouse., PMID:25012520

The electrogenic cardiac sodium bicarbonate co-transporter (NBCe1) contributes to the reperfusion injury., PMID:24721237

Endocrine regulation of carbonate precipitate formation in marine fish intestine by stanniocalcin and PTHrP., PMID:24501133

Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na⁺-HCO₃⁻ cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: role of the renin-angiotensin system., PMID:24253522

Lubiprostone targets prostanoid signaling and promotes ion transporter trafficking, mucus exocytosis, and contractility., PMID:22923315

Long-term cultivation of human corneal endothelial cells by telomerase expression., PMID:22575565

Determination of membrane protein transporter oligomerization in native tissue using spatial fluorescence intensity fluctuation analysis., PMID:22558387

Binding of carbonic anhydrase IX to extracellular loop 4 of the NBCe1 Na+/HCO3- cotransporter enhances NBCe1-mediated HCO3- influx in the rat heart., PMID:22538240

Expression of OAT1 and OAT3 in differentiating proximal tubules of the mouse kidney., PMID:19924639

Expression of the electrogenic Na+-HCO3--cotransporter NBCe1 in tumoral insulin-producing BRIN-BD11 cells., PMID:19710533

Electrogenic NBCe1 (SLC4A4), but not electroneutral NBCn1 (SLC4A7), cotransporter undergoes cholinergic-stimulated endocytosis in salivary ParC5 cells., PMID:18815229

Localization of electrogenic Na/bicarbonate cotransporter NBCe1 variants in rat brain., PMID:18582537

Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues., PMID:17715183

Distinct expression and subcellular localization patterns of Na+/HCO3- cotransporter (SLC 4A4) variants NBCe1-A and NBCe1-B in mouse brain., PMID:17433553

Identification of a novel signal in the cytoplasmic tail of the Na+:HCO3- cotransporter NBC1 that mediates basolateral targeting., PMID:17182531

Evidence against a direct interaction between intracellular carbonic anhydrase II and pure C-terminal domains of SLC4 bicarbonate transporters., PMID:17090540

Localization of NBC1 variants in rat kidney., PMID:16785749

Role of NH(2) and COOH termini in targeting, stability, and activity of sodium bicarbonate cotransporter 1., PMID:16622177

Inhibition of renal Na+/H+ exchange in cadmium-intoxicated rats., PMID:15781297

Sodium coupled bicarbonate transporters in the kidney, an update., PMID:15283764

Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis., PMID:15085340

Differential expression of electrogenic NBC1 (SLC4A4) variants in rat kidney and pancreas., PMID:14733916

Localization of NBC-1 variants in human kidney and renal cell carcinoma., PMID:14559244

Altered expression of renal acid-base transporters in rats with lithium-induced NDI., PMID:12944321

Identification and cloning of the Na/HCO(3-) cotransporter (NBC) in human corneal endothelium., PMID:12907161

Localization of Na+-HCO-3 cotransporter (NBC-1) variants in rat and human pancreas., PMID:12444017

Expression of a sodium bicarbonate cotransporter in human parotid salivary glands., PMID:11743927

Coordinated down-regulation of NBC-1 and NHE-3 in sodium and bicarbonate loading., PMID:11703600

Immunolocalization of electrogenic sodium-bicarbonate cotransporters pNBC1 and kNBC1 in the rat eye., PMID:11592950

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Anti-Human SLC4A4 Polyclonal Antibody.pdf