Catalog No.
PHF39101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RAB8A (Lys21-Ser181).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
RAB8, MEL, Ras-related protein Rab-8A, Oncogene c-mel, RAB8A
Purification
Purified by antigen affinity column.
Accession
P61006
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Knockout of DLIC1 leads to retinal cone degeneration via disturbing Rab8 transport in zebrafish., PMID:36682603
An efficient combination immunotherapy for antitumor immunity without accelerating cardiac allograft rejection., PMID:36517459
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms., PMID:33459343
The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human., PMID:29743203
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase., PMID:29127256
ARHGEF10 directs the localization of Rab8 to Rab6-positive executive vesicles., PMID:27550519
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1., PMID:26471730
The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation., PMID:25967552
E50K-OPTN-induced retinal cell death involves the Rab GTPase-activating protein, TBC1D17 mediated block in autophagy., PMID:24752605
Functional analysis of novel Rab GTPases identified in the proteome of purified Legionella-containing vacuoles from macrophages., PMID:24373249
LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route., PMID:24209575
RAB8 enhances TMEM205-mediated cisplatin resistance., PMID:21969054
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1., PMID:21378754
Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome., PMID:21273506
Identification and characterisation of novel Mss4-binding Rab GTPases., PMID:21194374
Rab8, a vesicular traffic regulator, is involved in dengue virus infection in HepG2 cells., PMID:18724065
Analysis of the role of Rab27 effector Slp4-a/Granuphilin-a in dense-core vesicle exocytosis., PMID:16473610
Rab8 regulates the actin-based movement of melanosomes., PMID:15673612
Expression and functional analyses of Rab8 and Rab11a in exocytic transport from trans-Golgi network., PMID:11210533
In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase., PMID:8643544
Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane., PMID:8408203
Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag., PMID:7688123
Expression of heterologous proteins in cultured rat hippocampal neurons using the Semliki Forest virus vector., PMID:8360951
For research use only. Not for human or drug use.
