Catalog No.
PHK20701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SIRT5 (Met40-Ser310).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SIR2-like protein 5, SIRT5, SIR2L5, Regulatory protein SIR2 homolog 5, NAD-dependent protein deacylase sirtuin-5, mitochondrial
Purification
Purified by antigen affinity column.
Accession
Q9NXA8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The Clinical Role of SIRT-3 in the Acute Rejection Process of Kidney Transplantation and Its Effects on Graft Outcomes: Evaluation of Biomarker Potential., PMID:40142268
Possible pathogenic mechanisms for doxorubicin-induced splenic atrophy in a human breast cancer xenograft mouse model., PMID:38943348
Exploring the role of mitochondrial proteins SIRT5 and MRPL33 through Mendelian randomization in primary biliary cholangitis., PMID:38857754
Inhibition of integrin receptors reduces extracellular matrix levels, ameliorating benign prostate hyperplasia., PMID:37659484
In-depth analysis of the Sirtuin 5-regulated mouse brain malonylome and succinylome using library-free data-independent acquisitions., PMID:36479818
Protein succinylation associated with the progress of hepatocellular carcinoma., PMID:36308411
Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells., PMID:34330933
Targeting a Sirt5-Positive Subpopulation Overcomes Multidrug Resistance in Wild-Type Kras Colorectal Carcinomas., PMID:29514096
Ethanol metabolism modifies hepatic protein acylation in mice., PMID:24073283
The first identification of lysine malonylation substrates and its regulatory enzyme., PMID:21908771
SIRT1 and SIRT5 activity expression and behavioral responses to calorie restriction., PMID:21826711
Mechanism-based affinity capture of sirtuins., PMID:21184005