Anti-Human NEFH Polyclonal Antibody

Catalog No.

PHC91701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NEFH (Glu331-Ile413).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

NFH, NF-H, KIAA0845, NEFH, Neurofilament heavy polypeptide, Neurofilament triplet H protein, 200 kDa neurofilament protein

Purification

Purified by antigen affinity column.

Accession

P12036

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognostic markers in amyotrophic lateral sclerosis., PMID:39575564

Charcot-Marie-Tooth type 2CC misdiagnosed as Chronic Inflammatory Demyelinating Polyradiculoneuropathy., PMID:39223423

Comparison of SNCG and NEFH Promoter-Driven Expression of Human SIRT1 Expression in a Mouse Model of Glaucoma., PMID:39177995

Early postnatal development of the primary visual areas 17 and 18 of the cat cerebral cortex: An SMI-32 study., PMID:39105520

Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain., PMID:37118836

Centripetal Nystagmus, Slow Saccades, Cerebellar Ataxia, and Parkinsonism in a Patient With Anti-GAD65-Associated Stiff Person Syndrome Spectrum Disorder., PMID:36728609

Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes., PMID:33749521

Heterochrony of postnatal accumulation of nonphosphorylated heavy-chain neurofilament by neurons of the cat dorsal lateral geniculate nucleus., PMID:32901924

Characterization of TAG-63 and its role on axonal transport in C. elegans., PMID:31622527

β-alanine supplementation induces taurine depletion and causes alterations of the retinal nerve fiber layer and axonal transport by retinal ganglion cells., PMID:31473259

Anti-CD52 antibody treatment depletes B cell aggregates in the central nervous system in a mouse model of multiple sclerosis., PMID:30098594

Epigenetic loss of heparan sulfate 3-O-sulfation sensitizes ovarian carcinoma to oncogenic signals and predicts prognosis., PMID:29732534

A novel histochemical method of simultaneous detection by a single- or double-immunofluorescence and Bielschowsky's silver staining in teased rat sciatic nerves., PMID:29596858

Nerve fibre layer degeneration and retinal ganglion cell loss long term after optic nerve crush or transection in adult mice., PMID:29452106

CSF neurofilament proteins as diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis., PMID:29322259

Changes in neurofilament 200 and tyrosine hydroxylase expression in the cardiac innervation of diabetic rats during aging., PMID:29175663

Geometric Navigation of Axons in a Cerebral Pathway: Comparing dMRI with Tract Tracing and Immunohistochemistry., PMID:28203748

Distribution of TTX-sensitive voltage-gated sodium channels in primary sensory endings of mammalian muscle spindles., PMID:28123009

HuD-mediated distinct BDNF regulatory pathways promote regeneration after nerve injury., PMID:28111162

The pathogenic relevance of αM-integrin in Guillain-Barré syndrome., PMID:27460017

Neurofilament heavy chain expression and neuroplasticity in rat auditory cortex after unilateral and bilateral deafness., PMID:27457532

Monoclonal antibody Py recognizes neurofilament heavy chain and is a selective marker for large diameter neurons in the brain., PMID:27311890

Increase of neurofilament-H protein in sensory neurons in antiretroviral neuropathy: Evidence for a neuroprotective response mediated by the RNA-binding protein HuD., PMID:27238228

Myelin injury induces axonal transport impairment but not AD-like pathology in the hippocampus of cuprizone-fed mice., PMID:27129150

Neuregulin-1β Regulates the migration of Different Neurochemical Phenotypic Neurons from Organotypically Cultured Dorsal Root Ganglion Explants., PMID:26093851

Moniliform deformation of retinal ganglion cells by formaldehyde-based fixatives., PMID:25283775

Bone marrow stromal cells promote neurite outgrowth of spinal motor neurons by means of neurotrophic factors in vitro., PMID:23832111

Neurophysiological and immunohistochemical studies of IgG anti-GM1 monoclonal antibody on neuromuscular transmission: effects in rat neuromuscular junctions., PMID:23820959

Neurofilament light and heavy subunits compared as therapeutic biomarkers in multiple sclerosis., PMID:23763388

Serum and cerebrospinal fluid heavy neurofilaments and antibodies against them in early multiple sclerosis., PMID:23632043

Immunohistochemical analysis of sympathetic involvement in the SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis., PMID:23607704

[Topography and morphometric characteristics of NF200(+)-neurons of the spinal cord gray matter after deafferentation with capsaicin]., PMID:24707735

Neuroendocrine cells are present in the domestic fowl ovary., PMID:23083425

Patients with Alzheimer disease have elevated intrathecal synthesis of antibodies against tau protein and heavy neurofilament., PMID:22948089

Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism., PMID:22941224

Expression of transient receptor potential ankyrin 1 in human dental pulp., PMID:22794211

In vivo effects of L1 coating on inflammation and neuronal health at the electrode-tissue interface in rat spinal cord and dorsal root ganglion., PMID:22750248

Accumulation of cortical hyperphosphorylated neurofilaments as a marker of neurodegeneration in multiple sclerosis., PMID:22723571

Involvement of endoplasmic reticulum stress in optic nerve degeneration following N-methyl-D-aspartate-induced retinal damage in mice., PMID:22674348

The spinal precerebellar nuclei: calcium binding proteins and gene expression profile in the mouse., PMID:22579822

Molecular and morphological evidence for cadaver vitreous-stimulated transformation of differentiation-competent retinal pigment epithelial cells into neuron-like cells., PMID:22578230

Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis., PMID:22561643

Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation., PMID:22544872

Elevated levels of S100B, tau and pNFH in cerebrospinal fluid are correlated with subtypes of Guillain-Barré syndrome., PMID:22526766

Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice., PMID:22369693

The involvement of neurofilament heavy chain phosphorylation in the maturation and degeneration of rat oocytes., PMID:22315443

Neuroplasticity of sensory and sympathetic nerve fibers in a mouse model of a painful arthritic joint., PMID:22246649

B-cell depletion attenuates white and gray matter pathology in marmoset experimental autoimmune encephalomyelitis., PMID:22002426

Increased nerve density in deep infiltrating endometriotic nodules., PMID:21150161

Delayed reinnervation by nonpeptidergic nociceptive afferents of the glabrous skin of the rat hindpaw in a neuropathic pain model., PMID:21120927

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