Catalog No.
PHK38101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human P2RX4 (Gln55-Asn338).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Purinergic receptor, P2RX4, P2X4, P2X purinoceptor 4, ATP receptor
Purification
Purified by antigen affinity column.
Accession
Q99571
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Bone marrow plasma cells require P2RX4 to sense extracellular ATP., PMID:38355795
Methods for studying P2X4 receptor ion channels in immune cells., PMID:38311008
Improvement of the affinity of an anti-rat P2X4 receptor antibody by introducing electrostatic interactions., PMID:34996944
The ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis through modulation of P2X4 receptor-dependent metabolism in myeloid cells., PMID:34548395
[Elucidation of Mast Cell Activation Mechanism Mediated by Purinergic Signaling]., PMID:34471006
Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats., PMID:34419102
Structural and Functional Features of the P2X4 Receptor: An Immunological Perspective., PMID:33897694
Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease., PMID:33838119
A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice., PMID:33336163
Extracellular ATP Augments Antigen-Induced Murine Mast Cell Degranulation and Allergic Responses via P2X4 Receptor Activation., PMID:32358018
Neurotoxic species of misfolded SOD1G93A recognized by antibodies against the P2X4 subunit of the ATP receptor accumulate in damaged neurons of transgenic animal models of amyotrophic lateral sclerosis., PMID:20084016
Role of mast cell activation in inducing microglial cells to release neurotrophin., PMID:20025063
Lymphocytes from P2X7-deficient mice exhibit enhanced P2X7 responses., PMID:19276178
Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?, PMID:19207989
ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes., PMID:18502908
Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury., PMID:18240312
Strong P2X4 purinergic receptor-like immunoreactivity is selectively associated with degenerating neurons in transgenic rodent models of amyotrophic lateral sclerosis., PMID:17990272
Purinergic 2X1 receptors mediate endothelial dependent vasodilation to ATP., PMID:17675587
Rat hepatocytes express functional P2X receptors., PMID:17597621
P2X4 is up-regulated in gingival fibroblasts after periodontal surgery., PMID:17251520
Post-Translational Modifications of the P2X(4) purinergic receptor subtype in the human placenta are altered in preeclampsia., PMID:16793133
Non-canonical YXXGPhi endocytic motifs: recognition by AP2 and preferential utilization in P2X4 receptors., PMID:15985462
The T-tubule membrane ATP-operated P2X4 receptor influences contractility of skeletal muscle., PMID:15857823
Electron microscopic localisation of P2X4 receptor subunit immunoreactivity to pre- and post-synaptic neuronal elements and glial processes in the dorsal vagal complex of the rat., PMID:15476696
OFF-cholinergic-pathway-selective localization of P2X2 purinoceptors in the mouse retina., PMID:15236470
The pattern of distribution of selected ATP-sensitive P2 receptor subtypes in normal rat kidney: an immunohistological study., PMID:14605489
Tissue distribution of P2X4 receptors studied with an ectodomain antibody., PMID:12845522
Identification of three genes of known function expressed by alveolar epithelial type I cells., PMID:12600825
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors., PMID:12383231
Identification of a non-canonical tyrosine-based endocytic motif in an ionotropic receptor., PMID:12105201
P2X receptor trafficking in neurons is subunit specific., PMID:12077178
Extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells., PMID:11788340
On the immunohistochemical distribution of ionotropic P2X receptors in the nucleus tractus solitarius of the rat., PMID:11738502
Identification of purinergic receptors in retinal ganglion cells., PMID:11483255
P2X receptor immunoreactivity in different arteries from the femoral, pulmonary, cerebral, coronary and renal circulations., PMID:11455204
Ionic selectivity of native ATP-activated (P2X) receptor channels in dissociated neurones from rat parasympathetic ganglia., PMID:11454961
Immunohistochemical identification of cells expressing ATP-gated cation channels (P2X receptors) in the adult rat thyroid., PMID:11430696
Distinct Localization of P2X receptors at excitatory postsynaptic specializations., PMID:11160443
The purinergic calcium channels P2X1,2,5,7 are down-regulated while P2X3,4,6 are up-regulated during apoptosis in the ageing rat prostate., PMID:11127979
Changes in the distribution of different subtypes of P2X receptor clusters on smooth muscle cells in relation to nerve varicosities in the pregnant rat urinary bladder., PMID:11068338
Distribution of P2X receptors in the rat adrenal gland., PMID:10639735
Structural motif and characteristics of the extracellular domain of P2X receptors., PMID:9245711
For research use only. Not for human or drug use.
