Catalog No.
PHA25302
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DVL1 (Ser413-Leu509).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DVL1, DSH homolog 1, Dishevelled-1, Segment polarity protein dishevelled homolog DVL-1
Purification
Purified by antigen affinity column.
Accession
O14640
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Increased activation of the WNT pathway in brain tissue from patients with cortical dysplasia type IIb., PMID:40055364
Spatiotemporal distribution of Wnt signaling pathway markers in human congenital anomalies of kidney and urinary tract., PMID:39908631
Copy number variation and clinical response to chemotherapy and bevacizumab in the Czech metastatic colorectal cancer patients., PMID:39174331
Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization., PMID:30309985
Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes., PMID:30067287
DNA methylation patterns associated with oxidative stress in an ageing population., PMID:27884142
Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia., PMID:27086035
Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1., PMID:26400647
Significant overexpression of DVL1 in Taiwanese colorectal cancer patients with liver metastasis., PMID:24129181
The functions of maternal Dishevelled 2 and 3 in the early Xenopus embryo., PMID:21618643
Down-regulation of NKD1 increases the invasive potential of non-small-cell lung cancer and correlates with a poor prognosis., PMID:21599923
Dishevelled family proteins are expressed in non-small cell lung cancer and function differentially on tumor progression., PMID:18692936
Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3., PMID:18093802
Novel immunohistochemical markers for the differentiation of lobular and ductal invasive breast carcinomas., PMID:17690741
Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease., PMID:17671721
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation., PMID:16446366
WNT/PCP signaling pathway and human cancer (review)., PMID:16273260
Interaction between Smad 3 and Dishevelled in murine embryonic craniofacial mesenchymal cells., PMID:15888125
WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer., PMID:14517837
Dishevelled-1 regulates microtubule stability: a new function mediated by glycogen synthase kinase-3beta., PMID:11018055
Beta-catenin, an inducer of uncontrolled cell proliferation and migration in malignancies, is localized in the cytoplasm of vascular endothelium during neovascularization after myocardial infarction., PMID:10980127
Interaction of Frizzled 7 and Dishevelled in Xenopus., PMID:10906785
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability., PMID:10330181
For research use only. Not for human or drug use.
