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Anti-Human OLIG2 Polyclonal Antibody

Catalog #:   PHG57001 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q13516
Overview

Catalog No.

PHG57001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human OLIG2 (Thr102-His180).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Protein kinase C-binding protein 2, bHLHe19, bHLHb1, PRKCBP2, Class E basic helix-loop-helix protein 19, Protein kinase C-binding protein RACK17, Oligodendrocyte transcription factor 2, BHLHE19, Oligo2, RACK17, BHLHB1, Class B basic helix-loop-helix protein 1, OLIG2

Purification

Purified by antigen affinity column.

Accession

Q13516

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Various lysates were subjected to SDS PAGE followed by western blot with OLIG2 antibody (PHG57001) at 1ug/mL .

    Lane 1: N2A cell lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 32 kDa
    Observed MW: 32 kDa
  • WESTERN-BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with OLIG2 antibody (PHG57001) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 23 kDa
    Observed MW: 23 kDa
  • Immunohistochemical
    Immunohistochemical analysis of rat brain stained for OLIG2 with PHG57001.
References

Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis., PMID:40173259

Melatonin ameliorates astrogliosis and microgliosis in a cuprizone demyelinating mouse model., PMID:39926210

MYB::QKI fusion-positive diffuse glioma of the cerebellum: A case report., PMID:39569742

Progesterone improves motor coordination impairments caused by postnatal hypoxic-ischemic brain insult in neonatal male rats., PMID:39181832

Revised Diagnosis From Histiocytic Neoplasm to Optic Chiasm Glioblastoma After Genetic Analysis., PMID:38926909

Low-Grade Glioma within Mature Cystic Teratoma in a Patient with Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report., PMID:38449876

Microglia/macrophage polarization regulates spontaneous remyelination in intermittent cuprizone model of demyelination., PMID:38234370

Deciphering the Action of Neuraminidase in Glioblastoma Models., PMID:37511403

[Alveolar rhabdomyosarcoma: novel surrogate markers associated with oncogenic translocation]., PMID:36785957

Utility of arterial spin labeling for objective assessment of intratumoral microvessels in diffuse hemispheric glioma, H3 G34R-mutant: A case report and literature review., PMID:36589502

Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease., PMID:36153599

Oligodendroglia Generated From Adult Rat Adipose Tissue by Direct Cell Conversion., PMID:35223826

Treatment With CD52 Antibody Protects Neurons in Experimental Autoimmune Encephalomyelitis Mice During the Recovering Phase., PMID:34975892

Oligosarcomas, IDH-mutant are distinct and aggressive., PMID:34967922

Isolation of Adult Human Astrocyte Populations from Fresh-frozen Cortex using Fluorescence-Activated Nuclei Sorting., PMID:33938880

Main Role of Antibodies in Demyelination and Axonal Damage in Multiple Sclerosis., PMID:33625628

Correlation Between Immunohistochemistry and Sequencing in H3G34-Mutant Gliomas., PMID:33428336

BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293

Oligodendrocyte Lineage Marker Expression in eGFP-GFAP Transgenic Mice., PMID:33346907

The presence of TIM-3 positive cells in WHO grade III and IV astrocytic gliomas correlates with isocitrate dehydrogenase mutation status., PMID:33244787

Radiological and Immunostaining Characteristics of H3.3 G34R-Mutant Glioma: A Report of 3 Cases and Review of the Literature., PMID:33227796

Glioblastoma TCGA Mesenchymal and IGS 23 Tumors are Identifiable by IHC and have an Immune-phenotype Indicating a Potential Benefit from Immunotherapy., PMID:32998960

Differential anatomical and cellular expression of lysophosphatidic acid receptor 1 in adult mouse brain., PMID:32718668

Distribution and localization of phosphatidylinositol 5-phosphate, 4-kinase alpha and beta in the brain., PMID:32449185

Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes., PMID:32383980

C9C5 positive mature oligodendrocytes are a source of Sonic Hedgehog in the mouse brain., PMID:32078657

Validating indicators of CNS disorders in a swine model of neurological disease., PMID:32074109

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course., PMID:31563982

OLIG2 is a novel immunohistochemical marker associated with the presence of PAX3/7-FOXO1 translocation in rhabdomyosarcomas., PMID:31493794

WHO grade has no prognostic value in the pediatric high-grade glioma included in the HERBY trial., PMID:31419298

Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells., PMID:30971893

Correlation of radiological and immunochemical parameters with clinical outcome in patients with recurrent glioblastoma treated with Bevacizumab., PMID:30877636

Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases., PMID:30658649

Anti-CD52 antibody treatment depletes B cell aggregates in the central nervous system in a mouse model of multiple sclerosis., PMID:30098594

Doublecortin-expressing cell types in temporal lobe epilepsy., PMID:30005693

Expression of Oligodendrocyte Precursor Cell Markers in Canine Oligodendrogliomas., PMID:29852819

PHOX2B is a reliable immunomarker in distinguishing peripheral neuroblastic tumours from CNS embryonal tumours., PMID:29758594

Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis., PMID:29708547

Blockade of sustained tumor necrosis factor in a transgenic model of progressive autoimmune encephalomyelitis limits oligodendrocyte apoptosis and promotes oligodendrocyte maturation., PMID:29690885

Neutralization of Interleukin-1β following Diffuse Traumatic Brain Injury in the Mouse Attenuates the Loss of Mature Oligodendrocytes., PMID:29690837

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment., PMID:29681511

Oxytocin alters cell fate selection of rat neural progenitor cells in vitro., PMID:29346405

Immunohistochemical comparative analysis of GFAP, MAP - 2, NOGO - A, OLIG - 2 and WT - 1 expression in WHO 2016 classified neuroepithelial tumours and their prognostic value., PMID:29258767

Spinal Cord Molecular and Cellular Changes Induced by Adenoviral Vector- and Cell-Mediated Triple Gene Therapy after Severe Contusion., PMID:29180963

Cellular reactions of the central nervous system., PMID:28987163

Effects of light emitting diode irradiation on neural differentiation of human umbilical cord-derived mesenchymal cells., PMID:28855704

Frozen tissue preparation for high-resolution multiplex histological analyses of human brain specimens., PMID:28795278

Expression of Oligodendrocyte Marker during Peripheral-Central Transitional Zone Formation of the Postnatal Mouse Cochlear Nerve., PMID:28695768

Adipose tissue-derived stromal cells (ADSC) express oligodendrocyte and myelin markers, but they do not function as oligodendrocytes., PMID:28620864

Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation., PMID:28326060

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human OLIG2 Polyclonal Antibody [PHG57001]
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