Anti-Human HEY2 Polyclonal Antibody

Catalog No.

PHK37701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HEY2 (Tyr111-His178).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

hHRT2, bHLHb32, Class B basic helix-loop-helix protein 32, CHF1, HERP, HEY2, Hairy/enhancer-of-split related with YRPW motif protein 2, GRL, BHLHB32, HRT-2, HES-related repressor protein 2, Protein gridlock homolog, Cardiovascular helix-loop-helix factor 1, Hairy and enhancer of split-related protein 2, HRT2, Hairy-related transcription factor 2, HERP1, HESR-2, hCHF1

Purification

Purified by antigen affinity column.

Accession

Q9UBP5

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice., PMID:38915069

Endothelial HIF2α suppresses retinal angiogenesis in neonatal mice by upregulating NOTCH signaling., PMID:38770916

NOTCH2 sensitizes the chondrocyte to the inflammatory response of tumor necrosis factor α., PMID:37865314

Leptin-induced Notch and IL-1 signaling crosstalk in endometrial adenocarcinoma is associated with invasiveness and chemoresistance., PMID:31367531

An antibody to Notch3 reverses the skeletal phenotype of lateral meningocele syndrome in male mice., PMID:31188489

IL6 blockade potentiates the anti-tumor effects of γ-secretase inhibitors in Notch3-expressing breast cancer., PMID:29027990

Endothelial Hey2 deletion reduces endothelial-to-mesenchymal transition and mitigates radiation proctitis in mice., PMID:28694461

Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop., PMID:25669984

TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways., PMID:25192910

Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme., PMID:23787764

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations., PMID:23388056

Differential gene expression in nuclear label-retaining cells in the developing mouse mammary gland., PMID:23199335

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis., PMID:22652674

A search for reliable molecular markers of prognosis in prostate cancer: a study of 240 cases., PMID:22586051

BMP9 and BMP10 are critical for postnatal retinal vascular remodeling., PMID:22566602

The leukemia associated nuclear corepressor ETO homologue genes MTG16 and MTGR1 are regulated differently in hematopoietic cells., PMID:22443175

Enhanced production of neuroprogenitors, dopaminergic neurons, and identification of target genes by overexpression of sonic hedgehog in human embryonic stem cells., PMID:21649559

Expression of Notch receptors, ligands, and target genes during development of the mouse mammary gland., PMID:21506125

Model of vasculogenesis from embryonic stem cells for vascular research and regenerative medicine., PMID:16754788

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