Anti-Human TRIM63 Polyclonal Antibody

Catalog No.

PHK37401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TRIM63 (Gly11-Arg112).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

IRF, RNF28, Iris RING finger protein, SMRZ, MURF1, MuRF-1, MuRF1, Striated muscle RING zinc finger protein, Tripartite motif-containing protein 63, TRIM63, E3 ubiquitin-protein ligase TRIM63, Muscle-specific RING finger protein 1, RING finger protein 28, RING-type E3 ubiquitin transferase TRIM63

Purification

Purified by antigen affinity column.

Accession

Q969Q1

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients., PMID:37943405

RANKL Mediates Muscle Atrophy and Dysfunction in a Cigarette Smoke-induced Model of Chronic Obstructive Pulmonary Disease., PMID:33689672

Emerging Strategies Targeting Catabolic Muscle Stress Relief., PMID:32630118

Adipocytes suppress differentiation of muscle cells in a co-culture system., PMID:30585366

Primary and Metastatic Melanoma With NTRK Fusions., PMID:29683819

Pathogenic role of anti-signal recognition protein and anti-3-Hydroxy-3-methylglutaryl-CoA reductase antibodies in necrotizing myopathies: Myofiber atrophy and impairment of muscle regeneration in necrotizing autoimmune myopathies., PMID:28224701

[Translocation of MuRF isoforms to nuclei in postural muscle during gravitational unloading]., PMID:25868327

Inhibition of activin A ameliorates skeletal muscle injury and rescues contractile properties by inducing efficient remodeling in female mice., PMID:24655377

Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors., PMID:24220501

Muscle-specific regulation of the mTOR signaling pathway in MuSK antibody seropositive (MuSK+) experimental autoimmune Myasthenia gravis (EAMG)., PMID:23933211

Construction, expression and characterization of a single chain variable fragment antibody against human myostatin., PMID:23919379

Developmental regulation of MURF E3 ubiquitin ligases in skeletal muscle., PMID:22426552

Joint inflammation alters gene and protein expression and leads to atrophy in the tibialis anterior muscle in rats., PMID:21959222

Epigallocatechin-3-gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia., PMID:21397390

High-mobility group box 1 release and redox regulation accompany regeneration and remodeling of skeletal muscle., PMID:21294652

MuSK antibody positive myasthenia gravis plasma modifies MURF-1 expression in C2C12 cultures and mouse muscle in vivo., PMID:16213598

Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I., PMID:15601779

Muscle-specific RING finger-2 (MURF-2) is important for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development., PMID:15199100

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