Anti-Human LIN28A Polyclonal Antibody

Catalog No.

PHK37001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LIN28A (Gln36-Gly111).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CSDD1, Zinc finger CCHC domain-containing protein 1, LIN28, LIN28A, Lin-28A, Protein lin-28 homolog A, ZCCHC1

Purification

Purified by antigen affinity column.

Accession

Q9H9Z2

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Lin28a forms an RNA-binding complex with Igf2bp3 to regulate m6A-modified stress response genes in stress granules of muscle stem cells., PMID:39021312

Prostate cancer research: tools, cell types, and molecular targets., PMID:38595814

Brain and Spinal Cord Tumors of Embryonic Origin., PMID:37452947

Embryonal tumors with multilayered rosettes, C19MC-altered or not elsewhere classified: Clinicopathological characteristics, prognostic factors, and outcomes of 17 children from 2018 to 2022., PMID:36353532

[Embryonal tumor with multilayered rosettes (ETMR): case report and literature review]., PMID:35758080

Let-7, Lin28 and Hmga2 Expression in Ciliary Epithelium and Retinal Progenitor Cells., PMID:33749722

Usefulness of PAX8 Immunohistochemistry in Adult Intraocular Tumor Diagnosis., PMID:33002562

A nanobody targeting the LIN28:let-7 interaction fragment of TUT4 blocks uridylation of let-7., PMID:32060122

MicroRNA Let-7 in B lymphocyte activation., PMID:31085798

Critical role of Lin28-TNFR2 signalling in cardiac stem cell activation and differentiation., PMID:30734494

Let-7 Suppresses B Cell Activation through Restricting the Availability of Necessary Nutrients., PMID:29337138

JAK2V617F influences epigenomic changes in myeloproliferative neoplasms., PMID:29066347

Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries., PMID:28892074

Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a., PMID:28577895

Intraocular Medulloepitheliomas and Embryonal Tumors With Multilayered Rosettes of the Brain: Comparative Roles of LIN28A and C19MC., PMID:25748578

Directed cardiomyogenesis of autologous human induced pluripotent stem cells recruited to infarcted myocardium with bioengineered antibodies., PMID:25132967

Reversible acetylation of Lin28 mediated by PCAF and SIRT1., PMID:24631505

[In vitro tumorigenicity tests for process control of health care products derived from human induced pluripotent stem cells]., PMID:24292187

TNF, acting through inducibly expressed TNFR2, drives activation and cell cycle entry of c-Kit+ cardiac stem cells in ischemic heart disease., PMID:23712715

A signature for induced pluripotent stem cell-associated genes in colorectal cancer., PMID:23307247

Systematic screens of proteins binding to synthetic microRNA precursors., PMID:23221640

LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR)., PMID:23161096

Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells., PMID:22615985

Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors., PMID:22532168

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