Catalog No.
PHH17301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ELAVL1 (Gly18-Gln198).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ELAV-like protein 1, HuR, ELAVL1, Hu-antigen R, HUR
Purification
Purified by antigen affinity column.
Accession
Q15717
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D., PMID:39809921
HuR (ELAVL1) regulates the CCHFV minigenome and HAZV replication by associating with viral genomic RNA., PMID:39348382
A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation., PMID:37925433
Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR., PMID:37848981
Different Genetic Signatures of Small-Cell Lung Cancer Characterize Anti-GABAB R and Anti-Hu Paraneoplastic Neurological Syndromes., PMID:37638563
Necessity of HuR/ELAVL1 for the activation-induced cytidine deaminase-dependent decrease in topoisomerase 1 in antibody diversification., PMID:37086201
The RNA binding protein human antigen R is a gatekeeper of liver homeostasis., PMID:34519101
CIRBP promotes ferroptosis by interacting with ELAVL1 and activating ferritinophagy during renal ischaemia-reperfusion injury., PMID:34114349
Assembly of Cytoplasmic Stress Granules in Placentas in Women with Preeclampsia., PMID:34101146
HuR up-regulates cell surface PD-L1 via stabilizing CMTM6 transcript in cancer., PMID:33649535
ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection., PMID:33637956
MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer., PMID:33273726
Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis., PMID:33200288
Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease., PMID:32240965
Human antigen R-regulated CCL20 contributes to osteolytic breast cancer bone metastasis., PMID:28851919
Data on isoaspartylation of neuronal ELAVL proteins., PMID:27924291
Cytoplasmic HuR Status Predicts Disease-free Survival in Resected Pancreatic Cancer: A Post-hoc Analysis From the International Phase III ESPAC-3 Clinical Trial., PMID:27893535
DO-RIP-seq to quantify RNA binding sites transcriptome-wide., PMID:27840290
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation., PMID:27595325
HuR in pheochromocytomas and paragangliomas - overexpression in verified malignant tumors., PMID:27357268
Expression of ARE-binding proteins AUF1 and HuR in follicular adenoma and carcinoma of thyroid gland., PMID:26925783
B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo., PMID:26320247
The RNA-binding protein HuR is essential for the B cell antibody response., PMID:25706746
A recently evolved class of alternative 3'-terminal exons involved in cell cycle regulation by topoisomerase inhibitors., PMID:24577238
Proteome-wide characterization of the RNA-binding protein RALY-interactome using the in vivo-biotinylation-pulldown-quant (iBioPQ) approach., PMID:23614458
Cooperative role of the RNA-binding proteins Hzf and HuR in p53 activation., PMID:21402775
High-constitutive HuR phosphorylation at Ser 318 by PKC{delta} propagates tumor relevant functions in colon carcinoma cells., PMID:21310943
HuR expression is a marker of poor prognosis in renal cell carcinoma., PMID:21161467
Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR., PMID:20086103
Melav2, an elav-like gene, is essential for spermatid differentiation in the flatworm Macrostomum lignano., PMID:19995429
Extensive association of HuR with hnRNP proteins within immunoselected hnRNP and mRNP complexes., PMID:19931428
HuR is exported to the cytoplasm in oral cancer cells in a different manner from that of normal cells., PMID:19513080
Angiotensin II induces renal plasminogen activator inhibitor-1 and cyclooxygenase-2 expression post-transcriptionally via activation of the mRNA-stabilizing factor human-antigen R., PMID:19246637
Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression., PMID:19130553
Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR., PMID:19010922
Enhancement of p53 expression in keratinocytes by the bioflavonoid apigenin is associated with RNA-binding protein HuR., PMID:18680106
Nuclear HuR accumulation through phosphorylation by Cdk1., PMID:18593881
UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes., PMID:18449856
Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule., PMID:18191643
Expression of HuR in Merkel cell carcinoma and in normal skin., PMID:18095988
Effects of infliximab therapy on gene expression levels of tumor necrosis factor alpha, tristetraprolin, T cell intracellular antigen 1, and Hu antigen R in patients with rheumatoid arthritis., PMID:17599736
Analysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expression., PMID:17178712
Early exposure to IL-4 stabilizes IL-4 mRNA in CD4+ T cells via RNA-binding protein HuR., PMID:16982877
Prognostic significance of cyclin A in gastric cancer., PMID:16708383
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR., PMID:16581801
Expression of CD83 is regulated by HuR via a novel cis-active coding region RNA element., PMID:16484227
Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR., PMID:16243808
The Xenopus ELAV protein ElrB represses Vg1 mRNA translation during oogenesis., PMID:16199879
New horizons for VEGF. Is there a role for nuclear localization?, PMID:15707649
Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses., PMID:15388877
For research use only. Not for human or drug use.
