Catalog No.
PHK35601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DGCR8 (Asp436-Lys752).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DGCRK6, Microprocessor complex subunit DGCR8, DiGeorge syndrome critical region 8, DGCR8, C22orf12
Purification
Purified by antigen affinity column.
Accession
Q8WYQ5
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Peptidylarginine deiminase 2 regulates expression of DGCR8 affecting miRNA biogenesis in gonadotrope cells., PMID:37310889
The microRNA processing subunit DGCR8 is required for a T cell-dependent germinal center response., PMID:36591274
MicroRNA and interleukin 6 interplay in the adipose tissue of rheumatoid arthritis patients., PMID:35579086
DGCR8 deficiency impairs macrophage growth and unleashes the interferon response to mycobacteria., PMID:33771876
METTL3 regulates inflammatory pain by modulating m6A-dependent pri-miR-365-3p processing., PMID:31914601
miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation., PMID:27880903
CRISPR/Cas9 Targets Chicken Embryonic Somatic Cells In Vitro and In Vivo and generates Phenotypic Abnormalities., PMID:27694906
Downregulated expression of Dicer1 predicts inferior survival in primary gastrointestinal diffuse large B-cell lymphoma treated with CHOP-like regimen and rituximab., PMID:25195038
Repression of GW/P body components and the RNAi microprocessor impacts primary ciliogenesis in human astrocytes., PMID:21880135
The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1., PMID:19906860
For research use only. Not for human or drug use.
