Catalog No.
PHK35501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CDKN2A (Val2-Arg54).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ARF, MLM, p14ARF, Cyclin-dependent kinase inhibitor 2A, CDKN2, CDKN2A, Alternative reading frame, Tumor suppressor ARF
Purification
Purified by antigen affinity column.
Accession
Q8N726
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
ctDNA Analysis in ERBB2-Amplified Colorectal Cancer: Biomarker Analysis of the MyPathway Trial., PMID:40512191
Biological and Clinical Relevance of Genetic Alterations in Peripheral T-cell Lymphomas., PMID:40416001
Molecular Mechanisms of Tumor Progression and Novel Therapeutic and Diagnostic Strategies in Mesothelioma., PMID:40362535
A model workflow for microfluidic enrichment and genetic analysis of circulating melanoma cells., PMID:40316673
Treatment outcomes of BTK inhibitors and venetoclax with or without anti-CD20 monoclonal antibody in relapsed or refractory mantle cell lymphoma., PMID:40278919
Pancreatic Cancer: Pathogenesis and Clinical Studies., PMID:40182139
Rare Metastatic Mesothelioma Occupying Intra-Atrial Cavity, Released by an Emergency Surgery: A Case Report and Literature Review., PMID:40034201
Gastric-type endocervical adenocarcinoma, superficial myofibroblastoma, sex cord-stromal tumors, and HSIL in Peutz-Jeghers syndrome: a rare case report, genetic characterization, and review of literature., PMID:40018404
Spitz Spindle Cell/Reed Nevus With SQSTM1 :: NTRK2 Fusion and Atypical Features in an Older Male Patient: A Case Report and Review of Literature., PMID:39980385
Performance analysis of Leica Biosystems p16 monoclonal antibody in oropharyngeal squamous cell carcinoma., PMID:39856694
Toripalimab plus chemotherapy for metastatic muscle-invasive bladder cancer with a high tumor proportion score: a case report., PMID:39744627
Efficacy of immune checkpoint inhibitors in pulmonary sarcomatoid carcinoma and predictive potential of mutated TP53., PMID:39736248
Genomic Biomarkers Associated with Enfortumab Vedotin Outcomes for Patients with Advanced Urothelial Carcinoma: Analysis of UNITE Study Data., PMID:39709257
Gene Expression Profiling of the Peritumoral Immune Cell Infiltrate of Penile Squamous Cell Carcinomas., PMID:39596210
Comprehensive Genomic Assessment of Advanced-Stage GI Stromal Tumors Using the Japanese National Center for Cancer Genomics and Advanced Therapeutics Database., PMID:39447098
MTAP and p16 IHC as Markers for CDKN2A/B Loss in Meningiomas., PMID:39409918
The road to overcome pancreatic cancer: Where are we?, PMID:39403527
Re-irradiation of anaplastic meningioma: higher dose and concomitant Bevacizumab may improve progression-free survival., PMID:39358739
Comparative analysis of PD-L1 expression and molecular alterations in primary versus metastatic lung adenocarcinoma: a real-world study in China., PMID:39323996
Targeting TGF-β signaling, oxidative stress, and cellular senescence rescues osteoporosis in gerodermia osteodysplastica., PMID:39234801
Advances in the understanding of molecular genetics and therapy of Richter transformation in chronic lymphocytic leukemia., PMID:39219481
cIMPACT-NOW update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas., PMID:39212325
Rare mediastinal small round cell melanoma with synovial sarcoma-like immunophenotype: A potential diagnostic pitfall., PMID:39151249
Clinical, genomic and immune microenvironmental determinants of nivolumab response in head and neck squamous cell carcinoma., PMID:39136017
Primary extraskeletal osteosarcomas of the pleura: A clinicopathological, immunohistochemical, and molecular analysis of 4 cases., PMID:39117026
[Clinicopathological features of metastatic melanoma in effusion cytology of serosal cavity]., PMID:39103266
PRAME and Historical Immunohistochemical Antibodies Ki-67, P16, and HMB-45 in Ambiguous Melanocytic Tumors., PMID:38916203
Case report: Pilomatrix carcinoma with PDL1 expression and CDKN2A aberrant., PMID:38873609
Characteristics of T cell premature senescence in maintenance hemodialysis patients., PMID:38850344
Durable radiologic and molecular complete response following nivolumab in an HNSCC patient with UV signature and HIV., PMID:38781626
P16-CD8-Ki67 Triple Algorithm for Prediction of CDKN2A Mutations in Patients with Multiple Primary and Familial Melanoma., PMID:38667459
Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer., PMID:38612819
Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL., PMID:38551807
Mutational, immune microenvironment, and clinicopathological profiles of diffuse large B-cell lymphoma and follicular lymphoma with BCL6 rearrangement., PMID:38462571
Clinical and molecular characteristics of Jordanian oropharyngeal cancer patients according to P16 expression: a retrospective study and a report of a novel biomarker., PMID:38459388
Impact of PIK3CA and cell cycle pathway genetic alterations on durvalumab efficacy in patients with head and neck squamous cell carcinoma: Post hoc analysis of TRIUMPH study., PMID:38458039
Pan-cancer Genomic Analysis of AXL Mutations Reveals a Novel, Recurrent, Functionally Activating AXL W451C Alteration Specific to Myxofibrosarcoma., PMID:38369783
Comparison of Immunohistochemistry, Next-generation Sequencing and Fluorescence In Situ Hybridization for Detection of MTAP Loss in Pleural Mesothelioma., PMID:38185249
Classification of gliomas based on genome-wide DNA methylation profiles and immunohistochemical analysis: a short study., PMID:39963031
Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL., PMID:38106221
Unveiling the role of MGMT and DAPK hypermethylation in response to anti-EGFR agents: Molecular insights for advancing HNSCC treatment., PMID:38095042
Genomic characterization of vulvar squamous cell carcinoma reveals differential gene expression based on clinical outcome., PMID:38086165
First-Line Ipatasertib, Atezolizumab, and Taxane Triplet for Metastatic Triple-Negative Breast Cancer: Clinical and Biomarker Results., PMID:38060199
miR-17-92 cluster-BTG2 axis regulates B-cell receptor signaling in mantle cell lymphoma., PMID:38050664
Loss of Histone H3K27 Trimethylation (H3K27me3) Expression as a Potential Diagnostic Pitfall in Sarcomatoid Carcinoma., PMID:37997394
Podocyte injury at young age causes premature senescence and worsens glomerular aging., PMID:37855038
A novel TPD52L2-ROS1 gene fusion expanding the molecular alterations in inflammatory myofibroblastic tumor: case report and literature review., PMID:37735390
Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer., PMID:37406106
Treatment of older patients with mantle cell lymphoma in the era of novel agents., PMID:37357622
Impact of Squamous Histology on Clinical Outcomes and Molecular Profiling in Metastatic Urothelial Carcinoma Patients Treated With Immune Checkpoint Inhibitors or Enfortumab Vedotin., PMID:37316414
For research use only. Not for human or drug use.
