Catalog No.
PHK35401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SIX2 (Met1-Asn189).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SIX2, Homeobox protein SIX2, Sine oculis homeobox homolog 2
Purification
Purified by antigen affinity column.
Accession
Q9NPC8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Generation of Hoxa11-3XFLAG and Hoxd11-3XFLAG alleles to investigate Hox11 genome-wide binding., PMID:40389054
SIX transcription factors are necessary for the activation of DUX4 expression in facioscapulohumeral muscular dystrophy., PMID:39627769
Characterizing post-branching nephrogenesis in the neonatal rabbit., PMID:37932368
Autoantibody profiling identifies predictive biomarkers of response to anti-PD1 therapy in cancer patients., PMID:32483460
iPSC-Derived Embryoid Bodies as Models of c-Met-Mutated Hereditary Papillary Renal Cell Carcinoma., PMID:31575031
Molecular characterization of nephron progenitors and their early epithelial derivative structures in the nephrogenic zone of the canine fetal kidney., PMID:31544449
Three Optimized Methods for In Situ Quantification of Progenitor Cell Proliferation in Embryonic Kidneys Using BrdU, EdU, and PCNA., PMID:31523438
Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors., PMID:30696889
Development of new method to enrich human iPSC-derived renal progenitors using cell surface markers., PMID:29686294
The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in KRAS-wild-type colorectal cancer., PMID:28435452
Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool., PMID:26116661
Mapping novel immunogenic epitopes in IgA nephropathy., PMID:25542908
DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret expression, and apoptosis., PMID:24699546
Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor properties., PMID:24055371
Wnt and BMP signaling cooperate with Hox in the control of Six2 expression in limb tendon precursor., PMID:23499659
Identification of multipotent stem/progenitor cells in murine sclera., PMID:21788434
Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm., PMID:21613322
Renal ontogeny in the rhesus monkey (Macaca mulatta) and directed differentiation of human embryonic stem cells towards kidney precursors., PMID:19500897
Tissue and developmental distribution of Six family gene products., PMID:9551859
For research use only. Not for human or drug use.
