Catalog No.
PHC13301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human S100A8 & S100A9 ([Leu2-Glu93] & [Met1-Pro114]).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CFAG, Leukocyte L1 complex light chain, Migration inhibitory factor-related protein 8, MRP-8, p8, S100 calcium-binding protein A8, Urinary stone protein band A, S100A8, CAGA, CFAG, MRP8, Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9, S100A9, CAGB, CFAG, MRP14
Purification
Purified by antigen affinity column.
Accession
P05109, P06702
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
RNA-seq reveals transcriptomic differences in circadian-related genes of the choroid plexus in a preclinical chronic migraine model., PMID:40501738
S100A8 Mediates Autophagy and Apoptosis in Ovarian Cancer Cells via the PI3K/Akt Pathway., PMID:40485527
In-silico identification and experimental validation of shared genes and pathways to decipher the molecular links between COPD and MASLD., PMID:40482557
S100a8 inhibitor Paquinimod attenuates coal dust-induced pulmonary fibrosis via blocking neutrophils-S100a8-Tlr4-macrophages signaling axis., PMID:40482449
Plasma proteomics identifies S100A8/A9 as a novel biomarker and therapeutic target for fulminant myocarditis., PMID:40480626
Transcriptomic insights into the mechanism of action of telomere-related biomarkers in rheumatoid arthritis., PMID:40475761
Impact of obesity on proteomic profiles of follicular fluid-derived small extracellular vesicles: A comparison between PCOS and non-PCOS women., PMID:40468347
Unraveling Laser-Induced peripheral Pain: Proteomic profiling and electrophysiological Dynamics in mice., PMID:40456478
B7-H3 Exacerbates Laser-induced Choroidal Neovascularization by Promoting Macrophage Recruitment and Polarization via S100A8/A9., PMID:40456216
Comparison of total calprotectin levels with S100A8 and S100A9 subunit levels in critically ill patients., PMID:40455718
Sea Cucumber Fucoidan Inhibits Helicobacter pylori Gastritis via MAPK/NF-κB Signaling and Gut Microbiota Modulation., PMID:40444701
Candidate Biomarkers for Hard-to-Heal Wounds Revealed by Single-Cell RNA Sequencing of Wound Fluid in Murine Wound Models., PMID:40444294
Identification of vitronectin as a potential non-invasive biomarker of metastatic breast cancer using a label-free LC-MS/MS approach., PMID:40442728
Characterizing age-related features for assessing biological age and characteristics in Xinjiang Brown cattle., PMID:40442598
Exploring the role of inflammation and proinflammatory proteins in coagulopathy during venovenous extracorporeal membrane oxygenation., PMID:40441037
Deciphering the Transcriptomic Complexity of Yak Skin Across Different Ages and Body Sites., PMID:40429746
Machine Learning-Driven Transcriptome Analysis of Keratoconus for Predictive Biomarker Identification., PMID:40426861
Comparative Proteomic Analysis of Osteoarthritis and Rheumatoid Arthritis: Identifying Potential Biomarkers., PMID:40426329
Low-Molecular-Weight Fucoidan Inhibits Thromboinflammation and Ameliorates Deep Vein Thrombosis via Targeting S100A8/A9., PMID:40422770
Genome-wide expression in human whole blood for diagnosis of latent tuberculosis infection: a multicohort research., PMID:40415930
Nervonic acid mitigates IMQ-triggered psoriasis in mice via inhibiting Th17/γδT17 cell invasion and modulating the gut microbiota., PMID:40397706
Synergistic inhibition of CitH3 and S100A8/A9: A novel therapeutic strategy for mitigating sepsis-induced inflammation and lung injury., PMID:40390290
Association of Elevated Serum S100A8/A9 Levels and Cognitive Impairment in Systemic Lupus Erythematosus Patients., PMID:40386900
Single cell sequencing technology reveals the correlation between B lymphocytes and vascular inflammatory symptoms of Kawasaki disease., PMID:40386362
Leukemia cells remodel bone marrow stromal cells to generate a protumoral microenvironment via the S100A8-NOX2-ROS signaling pathway., PMID:40382430
Calprotectin inhibition attenuates silica-induced lung fibrosis., PMID:40381145
Acute-phase proteins as biomarkers of inflammation in HIV patients with latent tuberculosis: a prospective study., PMID:40370442
Generalized gingivitis-related salivary proteomic profile in pregnant women with obesity: insights into biological mechanisms assessed by Tandem Mass Spectrometry., PMID:40366920
Development and validation of an early diagnosis model for severe mycoplasma pneumonia in children based on interpretable machine learning., PMID:40361124
In vivo RNAi screen and validation reveals Ngp, Hba-a1, and S100a8 as novel inhibitory targets on T lymphocytes in liver cancer., PMID:40352930
Protein Biomarkers in Venous Leg Ulcer Fluid: A Systematic Review., PMID:40342218
Post-burn lung inflammation is associated with induction of pulmonary cathelicidin-related antimicrobial peptide and S100a8 in mice., PMID:40341915
Exhaled breath protein composition in patients hospitalised during the first wave of COVID-19., PMID:40341493
Integrated multiomics and Mendelian randomization identify CHIT1 as a novel sepsis biomarker and therapeutic target., PMID:40325173
Calprotectin as a sepsis diagnostic marker in critical care: a retrospective observational study., PMID:40319081
Zebrafish do not have a calprotectin ortholog., PMID:40315184
Machine learning based identification of anoikis related gene classification patterns and immunoinfiltration characteristics in diabetic nephropathy., PMID:40312440
Analysis of the Expression Profile in COVID-19 Patients in the Russian Population Considering Disease Severity, Mortality, and Cytokine Storm., PMID:40299430
Enhanced Immunity and Infection Resistance in Mice Through Co-Expression of Porcine IL-3, IL-7, and IL-15 Fusion Molecules in Yarrowia lipolytica., PMID:40282231
Geniposide via enema alleviates colitis by modulating intestinal flora and bile acid metabolites, inhibiting S100A8/S100A9/NF-κB, and promoting TGR5 inhibition of NLRP3 inflammasome., PMID:40279965
Temporal mineralocorticoid receptor activation regulates the molecular clock and transcription of cardiovascular disease modulators in myeloid cells., PMID:40272082
S100A8/A9 high-expression macrophages mediate renal tubular epithelial cell damage in acute kidney injury following acute type A aortic dissection surgery., PMID:40270593
Targeting Calprotectin S100A8/A9 to Overcome AML Progression in DNMT3A-Mutant Cells., PMID:40266434
Shared Mechanisms in Cancer and Cardiovascular Disease: S100A8/9 and the NLRP3 Inflammasome: JACC: CardioOncology State-of-the-Art Review., PMID:40260700
The Impact of Recreational Diving to a Depth of 40 m on Selected Intracellular DAMPs., PMID:40243713
Plasma Proteomics of the Fontan Circulation Reveal Signatures of Oxidative Stress and Cell Death., PMID:40235440
Identification of the potential role of PANoptosis-related genes in burns via bioinformatic analyses and experimental validation., PMID:40233527
Reading of human acute immune dynamics in omicron SARS-CoV-2 breakthrough infection., PMID:40231451
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
Identification of Crohn's Disease-Related Biomarkers and Pan-Cancer Analysis Based on Machine Learning., PMID:40224483
For research use only. Not for human or drug use.
