Catalog No.
PHA12001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GFRA2 (Asp226-Ser444).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TGF-beta-related neurotrophic factor receptor 2, RETL2, GDNFR-alpha-2, GFRA2, GFR-alpha-2, Neurturin receptor alpha, TRNR2, GDNF receptor beta, GDNF family receptor alpha-2, NRTNR-alpha, RET ligand 2, NTNR-alpha, GDNFRB, GDNF receptor alpha-2, GDNFR-beta
Purification
Purified by antigen affinity column.
Accession
O00451
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A Multiplex Thyroid-Specific Assay for Quantification of Circulating Thyroid Cell-Free RNA in Plasma of Thyroid Cancer Patients., PMID:34512731
Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling., PMID:29414779
Paired Expression Analysis of Tumor Cell Surface Antigens., PMID:28871274
Role of neurturin in spontaneous itch and increased nonpeptidergic intraepidermal fiber density in a mouse model of psoriasis., PMID:28825602
Immunohistological analysis of neurturin and its receptors in human cochlea., PMID:24139947
Increased Th2 cytokine secretion, eosinophilic airway inflammation, and airway hyperresponsiveness in neurturin-deficient mice., PMID:21508262
Absence of pain with hyperhidrosis: a new syndrome where vascular afferents may mediate cutaneous sensation., PMID:19836135
Specificity in the crosstalk of TGFbeta/GDNF family members is determined by distinct GFR alpha receptors., PMID:17953664
Ret, GFRalpha-1, GFRalpha-2 and GFRalpha-3 receptors in the human hippocampus and fascia dentata., PMID:16002253
Expression of neurturin, glial cell line-derived neurotrophic factor, and their receptor components in light-induced retinal degeneration., PMID:15037593
Epitope-tagged recombinant AAV vectors for expressing neurturin and its receptor in retinal cells., PMID:11239244
Dual fluorescent in situ hybridization and immunohistochemical detection with tyramide signal amplification., PMID:10990490
Expression patterns of neurturin and its receptor components in developing and degenerative mouse retina., PMID:10067959
Age-dependent differences in the effects of GDNF and NT-3 on the development of neurons and glia from neural crest-derived precursors immunoselected from the fetal rat gut: expression of GFRalpha-1 in vitro and in vivo., PMID:9882478
For research use only. Not for human or drug use.
