Catalog No.
YHE91301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys69-Lys285
Predicted molecular weight
26.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52272
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HNRPM, Heterogeneous nuclear ribonucleoprotein M, hnRNP M, NAGR1, HNRNPM
hnRNPM regulates influenza A virus replication through distinct mechanisms in human and avian cells: implications for cross-species transmission., PMID:40434105
METTL3-dependent m6A modification of GHR mRNA regulates mitochondrial function through mitochondrial biogenesis during myoblast differentiation., PMID:40344709
HnRNPM inhibits pseudorabies virus replication by inducing apoptosis in infected cells., PMID:40068468
SUMOylated hnRNPM suppresses PFKFB3 phosphorylation to regulate glycolysis and tumorigenesis., PMID:39983892
circ_0004662 contributes to colorectal cancer progression by interacting with hnRNPM., PMID:39821691
HnRNPM modulates alternative splicing in germ cells by recruiting PTBP1., PMID:39780247
RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I., PMID:39707025
5'-tRNAGly(GCC) halves generated by IRE1α are linked to the ER stress response., PMID:39468069
FMRP protects breast cancer cells from ferroptosis by promoting SLC7A11 alternative splicing through interacting with hnRNPM., PMID:39388855
Pathogenic gene connections in type 2 diabetes and non-alcoholic fatty liver disease: a bioinformatics analysis and mouse model investigations experiments., PMID:39107295
Regulatory role of lncH19 in RAC1 alternative splicing: implication for RAC1B expression in colorectal cancer., PMID:39098911
Oncogenic LINC00698 suppresses apoptosis of melanoma stem cells to promote tumorigenesis via LINC00698-miR-3132-TCF7/hnRNPM axis., PMID:39068483
PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression., PMID:39034402
Genetic and clinical characteristics of acute B-cell lymphoblastic leukemia with MEF2D fusions and report of two novel MEF2D rearrangements., PMID:38990294
ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins., PMID:38896448
hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing., PMID:38815579
KIS counteracts PTBP2 and regulates alternative exon usage in neurons., PMID:38597390
Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression., PMID:38589732
Study on the interaction protein of transcription factor Smad3 based on TurboID proximity labeling technology., PMID:38537808
Circular RNA-circLRP6 protects cardiomyocyte from hypoxia-induced apoptosis by facilitating hnRNPM-mediated expression of FGF-9., PMID:38105623
4.5SH RNA counteracts deleterious exonization of SINE B1 in mice., PMID:38096826
Transcriptome analyses reveal key roles of alternative splicing regulation in atlantic salmon during the infectious process of Piscirickettsiosis disease., PMID:38058636
Knockdown of HNRNPM inhibits the progression of glioma through inducing ferroptosis., PMID:38016815
Construction of predictive ceRNA network and identification of the patterns of immune cells infiltrated in Graves' ophthalmopathy., PMID:37875358
Super Enhancer-Regulated LncRNA LINC01089 Induces Alternative Splicing of DIAPH3 to Drive Hepatocellular Carcinoma Metastasis., PMID:37756562
The bovine leukemia virus-derived long non-coding RNA AS1-S binds to bovine hnRNPM and alters the interaction between hnRNPM and host mRNAs., PMID:37671887
Quantitative phosphoproteomics reveals molecular pathway network alterations in human early-stage primary hepatic carcinomas: potential for 3P medical approach., PMID:37605650
hnRNPM suppressed IRF7-mediated IFN signaling in the antiviral innate immunity in triploid hybrid fish., PMID:37586670
A risk score combining co-expression modules related to myeloid cells and alternative splicing associates with response to PD-1/PD-L1 blockade in non-small cell lung cancer., PMID:37492578
Novel HNRNPM::LEUTX fusion resulting from chromothripsis of chromosome 19 in a pediatric undifferentiated small round cell neoplasm., PMID:37366242
A sensory neuron-specific long non-coding RNA reduces neuropathic pain by rescuing KCNN1 expression., PMID:37012681
circPTPN12 promotes the progression and sunitinib resistance of renal cancer via hnRNPM/IL-6/STAT3 pathway., PMID:37002206
LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity., PMID:36865202
A global study for acute myeloid leukemia with RARG rearrangement., PMID:36799929
Single-Cell Transcriptome Analysis Reveals Paraspeckles Expression in Osteosarcoma Tissues., PMID:36507075
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression., PMID:36496136
Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease., PMID:36417528
Genome-wide association study of fasting proinsulin, fasting insulin, 2-hour postprandial proinsulin, and 2-hour postprandial insulin in Chinese Han people., PMID:35971929
Downregulation of HNRNPM inhibits cell proliferation and migration of hepatocellular carcinoma through MAPK/AKT signaling pathway., PMID:35966311
SILAC kinase screen identifies potential MASTL substrates., PMID:35732702
A short report of novel RARG-HNRNPM fusion gene in resembling acute promyelocytic leukemia., PMID:35544458
HNRNPM Regulates HCC Tumorigenesis and Cancer Stemness: Identification of a Novel Therapeutic Target?, PMID:35245497
Targeting HNRNPM Inhibits Cancer Stemness and Enhances Antitumor Immunity in Wnt-activated Hepatocellular Carcinoma., PMID:35158098
CircURI1 interacts with hnRNPM to inhibit metastasis by modulating alternative splicing in gastric cancer., PMID:34385309
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells., PMID:34294847
RNA-binding motif protein RBM47 promotes tumorigenesis in nasopharyngeal carcinoma through multiple pathways., PMID:34274258
RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners., PMID:34244793
The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis., PMID:34145290
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness., PMID:34075878
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4., PMID:33837664
For research use only. Not for human or drug use.
