Catalog No.
YHH07501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn11-Ser173
Predicted molecular weight
19.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15366
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2
Acteoside ameliorates hepatocyte ferroptosis and hepatic ischemia-reperfusion injury via targeting PCBP2., PMID:40486855
PCBP2 in gastrointestinal cancers: fundamental mechanism and clinical potential., PMID:40481884
RNA binding proteins PCBP1 and PCBP2 regulate pancreatic β cell translation., PMID:40451383
Research on iron regulatory erythroid factors in children with β-thalassemia., PMID:40103337
PCBP2 as an intrinsic agi ng factor regulates the senescence of hBMSCs through the ROS-FGF2 signaling axis., PMID:40053388
PCBP2 promotes immune evasion via cGAS-STING pathway in biochemical recurrence of prostate cancer., PMID:40051782
RETRACTION: Role of miR-490-3p in Blocking Bladder Cancer Growth Through Targeting the RNA-Binding Protein PCBP2., PMID:40035239
PCBP2-dependent secretion of miRNAs via extracellular vesicles contributes to the EGFR-driven angiogenesis., PMID:39816681
Identification and validation of a novel defined stress granule-related gene signature for predicting the prognosis of ovarian cancer via bioinformatics analysis., PMID:39809219
Role of PCBP2 in regulating nanovesicles loaded with curcumin to mitigate neuroferroptosis in neural damage caused by heat stroke., PMID:39731111
PCBP2 stabilizes TROAP to promote the malignant progression of gastric cancer., PMID:39586843
PCBP1/2 and TDP43 Function as NAT10 Adaptors to Mediate mRNA ac4C Formation in Mammalian Cells., PMID:39556689
HNF4A-AS1 inhibits the progression of hepatocellular carcinoma by promoting the ubiquitin-modulated degradation of PCBP2 and suppressing the stability of ARG2 mRNA., PMID:39430249
Translation of Overlapping Open Reading Frames Promoted by Type 2 IRESs in Avian Calicivirus Genomes., PMID:39339889
Duck hepatitis A virus utilizes PCBP2 to facilitate viral translation and replication., PMID:39300570
Transcriptomic Alterations in Spliceosome Components in Advanced Heart Failure: Status of Cardiac-Specific Alternative Splicing Factors., PMID:39273537
Curcumin nanoparticles in heat stroke management., PMID:39267043
Circ_0005397 inhibits ferroptosis of pancreatic cancer cells by up-regulating PCBP2 through KAT6A/H3K9Ac., PMID:39235355
Poly(rC)-Binding Protein 2 Does Not Directly Participate in HCV Translation or Replication, but Rather Modulates Genome Packaging., PMID:39205194
Overexpression of long noncoding RNA DUXAP8 inhibits ER-phagy through activating AKT/mTOR signaling and contributes to preeclampsia., PMID:39120751
Down-regulation of PCBP2 suppresses the invasion and migration of trophoblasts via the WNT5A/ROR2 pathway in preeclampsia†., PMID:39115369
Structural basis for a highly conserved RNA-mediated enteroviral genome replication., PMID:39036953
ELF5-Regulated lncRNA-TTN-AS1 Alleviates Myocardial Cell Injury via Recruiting PCBP2 to Increase CDK6 Stability in Myocardial Infarction., PMID:39034459
Identification of differentially expressed genes of blood leukocytes for Schizophrenia., PMID:38988837
Burden re-analysis of neurodevelopmental disorder cohorts for prioritization of candidate genes., PMID:38965372
RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose., PMID:38950317
Follicular fluid-derived exosomal HMOX1 promotes granulosa cell ferroptosis involved in follicular atresia in geese (Anser cygnoides)., PMID:38943808
UKLF/PCBP2 axis governs the colorectal cancer development by transcriptionally activating SLC39A4., PMID:38768927
Association of poly(rC)-binding protein-2 with sideroflexin-3 through TOM20 as an iron entry pathway to mitochondria., PMID:38599240
The RNA secondary structure of androgen receptor-FL and V7 transcripts reveals novel regulatory regions., PMID:38554103
Elaborate cooperation of poly(rC)-binding proteins 1/2 and glutathione in ferroptosis induced by plasma-activated Ringer's lactate., PMID:38325565
Amyotrophic lateral sclerosis associated disturbance of iron metabolism is blunted by swim training-role of AKT signaling pathway., PMID:38171451
Glycine recalibrates iron homeostasis of lens epithelial cells by blocking lysosome-dependent ferritin degradation., PMID:38042221
Binding of microRNA-122 to the hepatitis C virus 5' untranslated region modifies interactions with poly(C) binding protein 2 and the NS5B viral polymerase., PMID:37941151
Identification of genetic biomarkers, drug targets and agents for respiratory diseases utilising integrated bioinformatics approaches., PMID:37925496
Data-Independent Acquisition Mass Spectrometry Analysis of FFPE Rectal Cancer Samples Offers In-Depth Proteomics Characterization of the Response to Neoadjuvant Chemoradiotherapy., PMID:37895091
Unveiling poly(rC)-binding protein 2 as the target protein for curcusone C against prostate cancer: mechanism validation through click chemistry-activity based proteomics profiling approach., PMID:37814239
Identification of alternative splicing associated with clinical features: from pan-cancers to genitourinary tumors., PMID:37810965
Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress., PMID:37736299
MiR-5195-3p targets the PCBP2/PI3K/AKT pathway to inhibit melanoma cell proliferation and migration., PMID:37662755
Genome-wide analysis of RNA-binding protein co-expression with alternative splicing events in acute respiratory distress syndrome following hematopoietic stem cell transplantation., PMID:37565892
The mRNA stability of NCAPG2, a novel contributor to breast invasive carcinoma, is enhanced by the RNA-binding protein PCBP2., PMID:37544634
Structural basis for cloverleaf RNA-initiated viral genome replication., PMID:37486760
Crystal structure of a highly conserved enteroviral 5' cloverleaf RNA replication element., PMID:37029118
Peptide-Based siRNA Nanocomplexes Targeting Hepatic Stellate Cells., PMID:36979383
The poly(C)-binding protein Pcbp2 is essential for CD4+ T cell activation and proliferation., PMID:36632062
Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of neuronal cytoplasmic inclusions., PMID:36592411
Elusive Trans-Acting Factors Which Operate with Type I (Poliovirus-like) IRES Elements., PMID:36555135
Long non-coding RNA TILR constitutively represses TP53 and apoptosis in lung cancer., PMID:36522487
A Bioinformatics Perspective on the Dysregulation of Ferroptosis and Ferroptosis-related Immune Cell Infiltration in Alzheimer's Disease., PMID:36438927
For research use only. Not for human or drug use.
