Catalog No.
YHK79701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr35-Lys276
Predicted molecular weight
28.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96B26
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Exosome component 8, EXOSC8, OIP-2, Opa-interacting protein 2, Exosome complex component RRP43, Ribosomal RNA-processing protein 43, OIP2, RRP43, p9
Disrupted maxillofacial, cardiovascular, and nervous development in washc5 knockout Zebrafish: Insights into 3C syndrome., PMID:39988189
A missense variant in EXOSC8 causes exon skipping and expands the phenotypic spectrum of pontocerebellar hypoplasia type 1C., PMID:38017281
ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells., PMID:37851577
EXOSC8 promotes colorectal cancer tumorigenesis via regulating ribosome biogenesis-related processes., PMID:36348012
A Two-Color Haploid Genetic Screen Identifies Novel Host Factors Involved in HIV-1 Latency., PMID:34872356
Detection of Melanogenesis and Anti-Apoptosis-Associated Melanoma Factors: Array CGH and PPI Mapping Integrating Study., PMID:34749602
13q Deletion Syndrome Involving RB1: Characterization of a New Minimal Critical Region for Psychomotor Delay., PMID:34573300
New subtype of PCH1C caused by novel EXOSC8 variants in a 16-year-old Spanish patient., PMID:34210538
Risk of sudden cardiac death in EXOSC5-related disease., PMID:34089229
Identification and Validation of a Novel RNA-Binding Protein-Related Gene-Based Prognostic Model for Multiple Myeloma., PMID:33981333
Bi-allelic missense variant, p.Ser35Leu in EXOSC1 is associated with pontocerebellar hypoplasia., PMID:33463720
RNA exosome mutations in pontocerebellar hypoplasia alter ribosome biogenesis and p53 levels., PMID:32527837
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities., PMID:32433464
Comprehensive characterization of the rRNA metabolism-related genes in human cancer., PMID:31548613
Co-expression network analysis identified key genes in association with mesenchymal stem cell osteogenic differentiation., PMID:31418071
Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy., PMID:29727687
Pontocerebellar hypoplasia type 1 for the neuropediatrician: Genotype-phenotype correlations and diagnostic guidelines based on new cases and overview of the literature., PMID:29656927
The RNA exosome and RNA exosome-linked disease., PMID:29093021
Global analysis of H3K27me3 as an epigenetic marker in prostate cancer progression., PMID:28403887
Altered RNA metabolism due to a homozygous RBM7 mutation in a patient with spinal motor neuropathy., PMID:27193168
Mutations in EXOSC2 are associated with a novel syndrome characterised by retinitis pigmentosa, progressive hearing loss, premature ageing, short stature, mild intellectual disability and distinctive gestalt., PMID:26843489
The exosome complex establishes a barricade to erythroid maturation., PMID:25115889
EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia., PMID:24989451
A new strategy for gene targeting and functional proteomics using the DT40 cell line., PMID:23892402
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex., PMID:20335458
A protein interaction framework for human mRNA degradation., PMID:15231747
A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity., PMID:11929972
For research use only. Not for human or drug use.
