Catalog No.
YHG70901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp69-Lys303
Predicted molecular weight
27.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14118
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dystrophin-associated glycoprotein 1, DAG1, Alpha-DG, Dystroglycan, Beta-DG
4D quantitative proteomics of ovarian granulosa cells reveals the involvement of oxidative phosphorylation in non-elderly women with diminished ovarian reserve., PMID:40394695
Live cell optical super-resolution microscopy of dystroglycan mutants as a model for dystroglycanopathies in multiple cell lines., PMID:40248434
Unlocking the genetic blueprint of duchenne muscular dystrophy: A personalized approach with MLPA and WES., PMID:40027239
Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts., PMID:39897774
A DOF transcriptional repressor-gibberellin feedback loop plays a crucial role in modulating light-independent seed germination., PMID:39876558
Laminin-dystroglycan mediated ferroptosis in hemorrhagic shock and reperfusion induced-cognitive impairment through AMPK/Nrf2., PMID:39864758
Identifying therapeutic targets for kidney stone disease through proteome-wide Mendelian randomization and colocalization analysis., PMID:39585470
Fat Mass- and Obesity-Associated Protein (FTO) Promotes the Proliferation of Goat Skeletal Muscle Satellite Cells by Stabilizing DAG1 mRNA in an IGF2BP1-Related m6A Manner., PMID:39337293
Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan., PMID:39305901
Proteome-wide mendelian randomization identifies therapeutic targets for nephrolithiasis., PMID:39237840
Expert panel curation of 31 genes in relation to limb girdle muscular dystrophy., PMID:39215466
Evaluating the causal effect of circulating proteome on the risk of inflammatory bowel disease-related traits using Mendelian randomization., PMID:39144148
The Proteomic Analysis of Chronic Migraine Exosomes Reveals Disease Patterns and Potential Biomarkers., PMID:39066974
[Clinical and bioinformatics analysis of the relationship between LAMA3 DNA methylation expression and platinum resistance and prognosis in epithelial ovarian cancer]., PMID:38951081
Tools for Cre-Mediated Conditional Deletion of Floxed Alleles from Developing Cerebellar Purkinje Cells., PMID:38777609
The missense mutation C667F in murine β-dystroglycan causes embryonic lethality, myopathy and blood-brain barrier destabilization., PMID:38616731
Tools for Cre-mediated conditional deletion of floxed alleles from developing cerebellar Purkinje cells., PMID:38585758
Dof1.7 and NIGT1 transcription factors mediate multilayered transcriptional regulation for different expression patterns of NITRATE TRANSPORTER2 genes under nitrogen deficiency stress., PMID:38523242
The Role of β-Dystroglycan in Nuclear Dynamics., PMID:38474395
Inhibitory CCK+ basket synapse defects in mouse models of dystroglycanopathy., PMID:38179984
DAG1 haploinsufficiency is associated with sporadic and familial isolated or pauci-symptomatic hyperCKemia., PMID:38177406
Proteomics Analysis of Serum Reveals Potential Biomarkers for Heart Failure Patients with Phlegm-Blood Stasis Syndrome., PMID:38048169
Genome-wide scan for runs of homozygosity in South American Camelids., PMID:37605116
A redundant transcription factor network steers spatiotemporal Arabidopsis triterpene synthesis., PMID:37188853
Circular RNA circ-TNRC6B inhibits the proliferation and invasion of esophageal squamous cell carcinoma cells by regulating the miR-452-5p/DAG1 axis., PMID:37014625
Differential Urinary Proteomic Analysis of High-Risk Cervical Intraepithelial Neoplasia., PMID:36768853
Involvement of abnormal dystroglycan expression and matriglycan levels in cancer pathogenesis., PMID:36494657
Exogenous laminin exhibits a unique vascular pattern in the brain via binding to dystroglycan and integrins., PMID:36463265
The many roles of dystroglycan in nervous system development and function: Dystroglycan and neural circuit development: Dystroglycan and neural circuit development., PMID:35770940
Genome-Wide Knockout Screen Identifies Human Sialomucin CD164 as an Essential Entry Factor for Lymphocytic Choriomeningitis Virus., PMID:35502904
Localized TPC1-mediated Ca2+ release from endolysosomes contributes to myoseptal junction development in zebrafish., PMID:35393618
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
A novel 1-bp deletion variant in DAG1 in Japanese familial asymptomatic hyper-CK-emia., PMID:35082294
Deficiency of Glycosylated α-Dystroglycan in Ventral Hippocampus Bridges the Destabilization of Gamma-Aminobutyric Acid Type A Receptors With the Depressive-like Behaviors of Male Mice., PMID:35063187
Urine-Derived Stem Cells Express 571 Neuromuscular Disorders Causing Genes, Making Them a Potential in vitro Model for Rare Genetic Diseases., PMID:34744760
Heparan sulfate proteoglycans serve as alternative receptors for low affinity LCMV variants., PMID:34648606
Novel Insight in Idiopathic Normal Pressure Hydrocephalus (iNPH) Biomarker Discovery in CSF., PMID:34360799
The extracellular matrix protein Agrin is expressed by osteoblasts and contributes to their differentiation., PMID:34223979
Crystal structures of β-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies., PMID:33825709
Role of kisspeptin on cell proliferation and steroidogenesis in luteal cells in vitro and in vivo., PMID:33784266
The Association Between β-Dystroglycan in Airway Smooth Muscle and Eosinophils in Allergic Asthma., PMID:33566255
NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes., PMID:33513091
Abnormal promoter DNA hypermethylation of the integrin, nidogen, and dystroglycan genes in breast cancer., PMID:33500458
The administration of antisense oligonucleotide golodirsen reduces pathological regeneration in patients with Duchenne muscular dystrophy., PMID:33407808
Genetic variations and clinical spectrum of dystroglycanopathy in a large cohort of Chinese patients., PMID:33200426
Characteristic Cochlear Hypoplasia in Patients with Walker-Warburg Syndrome: A Radiologic Study of the Inner Ear in α-Dystroglycan-Related Muscular Disorders., PMID:33122211
Plant-specific Dof transcription factors VASCULAR-RELATED DOF1 and VASCULAR-RELATED DOF2 regulate vascular cell differentiation and lignin biosynthesis in Arabidopsis., PMID:32740898
Reporting one very rare pathogenic variation c.1106G>A in POMT2 gene., PMID:32494558
Congenital hearing impairment associated with peripheral cochlear nerve dysmyelination in glycosylation-deficient muscular dystrophy., PMID:32453729
Clinical and electrophysiological evaluation of myasthenic features in an alpha-dystroglycanopathy cohort (FKRP-predominant)., PMID:32115343
For research use only. Not for human or drug use.
